Tag: transcriptional regulation

In preclinical lung squamous cell carcinoma models, GATA6 directly represses BMP2, while elevated BMP2 activates ERK1/2 signaling and promotes tumor-cell ...

A study in Jurkat T cells found that activated STAT3 binds the Ets-2 promoter, reduces expression of a transcriptional silencer, ...

Three WRKY transcription factors activate PsDFR2 and promote anthocyanin accumulation, helping explain the molecular basis of red pigmentation in tree ...

Researchers have catalogued 47 WRKY transcription factor genes in Codonopsis pilosula and linked specific members, including Cpi05G005333-I, to the herb's ...

A short isoform of the BRD4 protein helps gastric cancer cells resist ferroptotic cell death by sustaining glutathione production, thereby ...

Researchers at South China Agricultural University report that the soybean VQ motif gene GmVQ32 enhances tolerance to both aluminium toxicity ...

New research reveals how nitrogen starvation, a cryptochrome photoreceptor, and humidity checkpoints govern the transcriptional program that drives spore formation ...

Researchers identified the GRAS transcription factor PmGRAS8 as a candidate activator of the phosphate-responsive PmSPX1 promoter in Masson pine, shedding ...

A new study shows that the transcription factor ELF4 activates the enzyme UGT8, reshaping sphingolipid metabolism to drive esophageal squamous ...

In a groundbreaking study poised to reshape our understanding of schizophrenia’s genetic underpinnings, researchers have identified functional variants at the ...

In the ever-evolving frontiers of molecular biology, the dynamic orchestration of gene expression remains a captivating enigma, particularly in the ...

In the evolving landscape of oncology research, the intricate molecular mechanisms that drive the progression of ovarian cancer continue to ...

In a groundbreaking study poised to reshape our understanding of early mammalian development, researchers have uncovered a pivotal role for ...

A groundbreaking study reveals the pivotal role of the transcription factor GLIS3 in orchestrating a fibrotic cell circuit linked to ...

In the realm of oncology, a persistent challenge has been the long-term neurotoxic consequences faced by patients undergoing chemotherapy. While ...

Recent advancements in cancer research have illuminated the complex nature of medulloblastoma, a malignant brain tumor primarily affecting children. In ...