No Evidence Links Adenovirus Infection to Vaccine-Induced Clotting
A perspective in Discover Viruses finds no evidence that natural adenovirus infections trigger vaccine-induced immune thrombotic thrombocytopenia in recipients of ...
Tag: Thrombocytopenia
Children With Uncorrected Cyanotic Heart Disease Show Significant Clotting Abnormalities
An observational case-control study shows that children with uncorrected congenital cyanotic heart disease experience significant coagulation factor prolongations, increased D-dimer ...
First Autochthonous Human SFTS Virus Cases Documented in Inner Mongolia
Researchers have documented the first laboratory-confirmed autochthonous human cases of severe fever with thrombocytopenia syndrome virus in Inner Mongolia alongside ...
Trastuzumab emtansine biosimilar shows real-world results in HER2-positive breast cancer in India
A retrospective Indian analysis of 101 patients reports real-world efficacy and safety outcomes for the trastuzumab emtansine biosimilar UJVIRA in ...
Detailed safety analysis shows sacituzumab tirumotecan manageable in metastatic triple-negative breast cancer
A post-hoc safety analysis of the phase 3 OptiTROP-Breast01 trial found that sacituzumab tirumotecan's key adverse events arose mainly in ...
Early dialysis tied to higher death risk in sepsis kidney injury study
A retrospective MIMIC-IV study of 629 sepsis-associated acute kidney injury patients found that starting continuous renal replacement therapy within 12 ...
Rare leukemia revealed by diffuse osteosclerosis on FDG-PET/CT
An FDG-PET/CT scan in a 64-year-old woman with fever of unknown origin revealed diffuse osteosclerosis and osteolytic lesions that led ...
Rapid Platelet Recovery With Cyclosporine and Romiplostim Enabled Gastric Cancer Surgery in Severe Aplastic Anemia
A case report describes how cyclosporine A and romiplostim rapidly raised platelet counts in a woman with severe aplastic anemia ...
Pacritinib After Ruxolitinib: Five-Case Saudi Series Reports Higher Blood Counts and Smaller Spleens
A five-patient case series from Saudi Arabia reports that pacritinib, used after prior ruxolitinib exposure in advanced myelofibrosis, was associated ...
Blood Counts Fall Uniformly During Peginterferon Therapy for Chronic Hepatitis B, Small Study Finds
An exploratory 21-patient cohort study documents near-universal declines in white blood cell, neutrophil, and platelet counts during peginterferon alfa-2b therapy ...
FAERS analysis identifies platelet and triglyceride signals for givinostat
A retrospective FAERS analysis of 321 givinostat reports identified platelet abnormalities and increased blood triglycerides as prominent safety signals but ...
Single-arm trial finds preliminary hetrombopag activity in gynecologic cancer
A small single-arm trial found preliminary platelet-recovery activity and no serious adverse events among 37 Chinese patients with gynecologic malignancies ...
Comparative study finds molecular differences in lupus-associated thrombocytopenia
A comparative study found differences in PVT1, miR-181a, RORγt, FOXP3 and circulating markers among patients with SLE-associated thrombocytopenia, patients with ...
Retrospective study of clinical predictors of PCR-confirmed CCHF in Iraq
A retrospective study of 806 suspected cases found clinical factors associated with PCR-confirmed Crimean-Congo hemorrhagic fever in southern Iraq.
Weil’s Syndrome Mimicked Acute Cholangitis in a Farmer With Leptospirosis
A case report of severe leptospirosis in a 35-year-old farmer found that Weil’s syndrome can mimic acute cholangitis despite the ...
Blood Cell Crashes After CAR-T Therapy Follow a Predictable Risk Score, Study Finds
A retrospective cohort study of 96 patients shows the CAR-HEMATOTOX score predicts severe neutropenia and thrombocytopenia after CAR-T cell therapy, ...
Blood Transfusions and Low Platelets Flag Bleeding Risk in Prostate Cancer Patients on Antithrombotics
For men with advanced prostate cancer approaching the end of life, a routine decision about whether to continue blood thinners ...
Chemotherapy Wrecks the Bone Marrow Ecosystem, Not Just Platelet Counts, Review Argues
A new review in Supportive Care in Cancer reframes chemotherapy-induced thrombocytopenia as a dual destruction of megakaryocytes and the bone ...
When Lupus Strikes the Brain’s Veins: Rare Childhood Stroke Clue Emerges
A Chinese case series of eleven children with lupus identifies headache, transverse sinus involvement, elevated CRP and thrombocytopenia as the ...
Rare Childhood Bleeding Disorder Traced to Two New ADAMTS13 Gene Variants
A Chinese pediatric case series has identified two previously unreported ADAMTS13 gene variants in children with hereditary thrombotic thrombocytopenic purpura, ...
