Circular RNA aptamers recruit natural ADAR1 to edit RNA with near-perfect efficiency
A new RNA editing platform called MARRS recruits the cell's own ADAR1 enzyme with engineered circular RNA aptamers, achieving up ...
Tag: off-target effects
CRISPR gene therapies face a reckoning with off-target genome edits
A new review maps the molecular, computational and experimental landscape of off-target CRISPR editing as gene therapies advance toward the ...
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