A Mendelian randomization analysis indicates that genetically predicted cathepsin levels are associated with risks of Alzheimer's disease and Parkinson's disease.
A review highlights how exercise-responsive non-coding RNAs regulate key cellular processes and offer potential as non-invasive biomarkers across neurodegenerative diseases ...
De novo designed microproteins, built computationally to bind toxic amyloid fibrils and restore mitochondrial function, are emerging as promising candidates ...
A new review proposes that migrasomes in the central nervous system act as either pathogenic drivers or protective factors depending ...
A new review in Discover Molecules synthesizes the chemistry, limited bioavailability, and gut-brain interactions of plant phenolic compounds, cautioning that ...
A new review outlines how misfolded protein aggregates activate the NLRP3 inflammasome and how prion-like ASC specks may shape neurodegenerative ...
A new review argues that the NF-κB1 subunit's p105 and p50 proteins act as context-dependent regulators of neuronal survival and ...
A computational model of Alzheimer's disease shows that adjusting short-term synaptic facilitation time constants can restore memory engram selectivity and ...
A new study shows the natural chalcone cardamonin calms LPS-activated microglia by suppressing the EGFR/PI3K/AKT1/ERK/NF-kappaB signaling axis, indirectly protecting SH-SY5Y ...
A survey of 55 Bulgarian patients found that 85.5 percent would use cannabidiol if recommended by a healthcare professional, despite ...
A new cost-effective workflow improves proteomic analysis of plasma and cerebrospinal fluid by optimizing protein depletion and digestion for high-throughput ...
A new review argues that the bottleneck for RNAi therapies in Alzheimer's, Parkinson's and Huntington's disease is not gene silencing ...
Artificial intelligence is quietly transforming two of the most intimate fields of medicine: neuroscience and psychology. A new editorial published ...
University of Ottawa researchers report that extracellular vesicles can ferry engineered antibodies across the blood-brain barrier, and that tagging disease ...
Researchers in New Delhi have developed a disposable paper-based electrochemical sensor that simultaneously detects Alzheimer's and Parkinson's disease biomarkers with ...
A computational study identifies plant-derived compounds, notably coumarin, as promising dual inhibitors of the ROCK1 and ROCK2 enzymes that regulate ...
A new review in the Journal of Translational Medicine charts how magnetic resonance spectroscopic imaging is evolving from static metabolite ...
A new explainable machine learning framework combining EEG signals with clinical data distinguishes Alzheimer's disease from frontotemporal dementia with 89.8 ...
In a groundbreaking new study published in Nature Communications in 2026, researchers have uncovered a promising therapeutic target that could ...
In a groundbreaking advancement set to transform the diagnosis and understanding of Parkinson’s disease, researchers have unveiled a comprehensive metabolomic ...
