New CRISPR genome editing system offers a wide range of versatility in human cells
'Prime editing' combines two key proteins and a new RNA to make targeted insertions, deletions, and all possible single-letter changes ...
Tag: Molecular Biology
Silencing RNA nanotherapy shows promise against pancreatic cancer
A Washington University-University of South Florida preclinical study finds that the novel nanoparticle delivers gene-level treatment to suppress KRAS-driven cancer ...
SciLifeLab and AstraZeneca use cryo-EM to advance biomedicine
Research team of Alexey Amunts in collaboration with AstraZeneca unravel the extracellular region of the receptor tyrosine kinase RET involved ...
Data mining applied to scholarly publications to finally reveal Earth’s biodiversity
Credit: P Kishor (Plazi) At a time when a million species are at risk of extinction, according to a recent ...
Salk scientists awarded $14.3 million to map circuitry for movement
Credit: Salk Institute LA JOLLA, CA--(October 18, 2019) A team of Salk scientists led by Professor Martyn Goulding has been ...
A compound effective to chemotherapy-resistant cancer cells identified
Credit: Hokkaido University A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs ...
Whole genome sequencing could help save pumas from inbreeding
Credit: Sebastian Kennerknecht When students at the University of California, Santa Cruz (UCSC) found a dead mule deer on campus, ...
A new approach to reconstructing protein evolution
UMass Amherst, University of Virginia scientists propose new, more focused methodCredit: UMass Amherst AMHERST, Mass. - There are an estimated ...
An evolution in the understanding of evolution
New modeling tool has implications for better understanding of diseaseCredit: UVA Engineering Remember domain, kingdom, phylum, class, order, family, genus, ...
New insights into the structure and function of Cdc34, a target for cancer therapeutics
Credit: Sarah Pack, Medical University of South Carolina Some of the greatest insights into cancer and how to treat it ...
Bone regrowth using ceramic substitute and E. coli-derived growth factors
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, October 16, 2019-Synthetic bone substitutes are promising materials for bone defect ...
CNIO researchers obtain the first mice born with hyper-long telomeres
The study shows that it is possible to extend life without any genetic modificationCredit: CNIO A chance finding ten years ...
X marks the spot: recombination in structurally distinct chromosomes
Credit: Hawley Lab KANSAS CITY, MO-Two years ago, scientists from the Stowers Institute for Medical Research reported the 3D structure ...
First Genome of Spotted Lanternfly Built from a Single Insect
Credit: ARS-USDA HILO, HAWAII, October 16, 2019--Agricultural Research Service (ARS) scientists, in cooperation with Pacific Biosciences and Penn State University, ...
Empty spaces, how do they make a protein unstable?
Partial unfolding of proteins may affect their stability and is a challenge in the industry. So how does a cavity ...
Gene mutation in the chloride channel triggers rare high blood pressure syndrome
Credit: Audrey H. Soria, FMP When the adrenal gland produces too much aldosterone, this often leads to high blood pressure ...
New journal to explore the ‘mysterious ecosystem’ in our gut
Credit: Cambridge University Press/Nutrition Society A new open access journal from Cambridge University Press, published in partnership with The Nutrition ...
SLAS Discovery releases special issue
'Membrane proteins: New approaches to probes, technologies and drug design' now availableCredit: David James Group Oak Brook, IL - October's ...
International consortium with CeMM PI Joanna Loizou receives ERC Synergy Grant
Credit: Steve P. Jackson, Joanna Loizou and Jacob Corn ERC Synergy Grants are intended to enable a minimum of two ...
Family of crop viruses revealed at high resolution for the first time
Credit: Univeristy of Leeds For the first-time we can take a molecular-level look at one of the world's deadliest crop ...
