Tag: microRNA

A single-centre study found serum miR-1287-5p elevated in knee osteoarthritis patients and showed in chondrocyte experiments that the microRNA promotes ...

Serum miR-125a-5p shows promise for predicting rheumatoid arthritis treatment response

A study of 137 rheumatoid arthritis patients found that low serum miR-125a-5p independently predicted failure to achieve clinical remission after ...

Small Follow-Up Study Tracks Child Development After High Prenatal Stress

Researchers at the University of Missouri have reported early results from a feasibility study that followed children whose mothers experienced ...

Chicory Root Compounds Linked to Gene and microRNA Networks in Mouse Data Analysis

A bioinformatic reanalysis of mouse microarray datasets links major chicory root compounds to distinct hub genes, signaling pathways, and predicted ...

Rising miR-618 Levels Linked to Severity in Neonatal Respiratory Distress Syndrome

A study of 110 newborns with NARDS finds elevated serum miR-618 associated with disease severity and lower 30-day survival, with ...

Blood MicroRNA Shows Diagnostic Promise and Regulatory Role in Coronary Atherosclerosis

A single-center case-control study found that serum miR-20a-5p was markedly reduced in patients with coronary atherosclerosis and showed moderate-to-high diagnostic ...

Blood microRNA patterns distinguish metabolic disease in people of any body weight

A study of 240 Qatari adults found that circulating microRNA signatures distinguish metabolically unhealthy from metabolically healthy individuals independent of ...

Single-cell map reveals how EV-derived miRNAs shape the liver cancer microenvironment

A computational analysis of single-cell RNA sequencing data maps 208 prognosis-linked miRNA-target pairs carried by extracellular vesicles in the hepatocellular ...

Elevated miR-183-5p Impairs Bone-Forming Stem Cells in Scoliosis

A study in BMC Medical Genomics finds that miR-183-5p is upregulated in the serum of adolescent idiopathic scoliosis patients, shows ...

MicroRNA miR-22-3p drives radiation resistance in glioblastoma by suppressing TET1

A new study finds that the microRNA miR-22-3p promotes glioblastoma radioresistance and downregulates the DNA demethylase TET1, while inhibiting it ...

Tiny RNA Molecule Shields Newborn Brains from Oxygen-Starved Cell Death

New rat and cell experiments show that the microRNA miR-7a-5p protects the neonatal brain from hypoxic-ischemic injury by suppressing PARP1-driven ...

MicroRNA changes persist in newborn blood after neonatal encephalopathy

A study of 66 newborns found that microRNA alterations linked to neonatal encephalopathy remain detectable in whole blood for up ...

MicroRNA miR-221-3p Linked to Increased Respiratory Risks in Children Undergoing General Anesthesia

High expression of microRNA-221-3p in the postoperative serum of children is associated with an increased risk of perioperative respiratory adverse ...

CHD9 3’UTR Regulates MicroRNAs to Protect Bone in Mice

A study in Scientific Reports shows that the CHD9 3'UTR sequesters specific microRNAs to regulate gene expression and ameliorate osteoporosis ...

MicroRNA miR-183-3p emerges as candidate regulator of ESR1 in colorectal cancer

An integrative analysis combining sequencing, Mendelian randomization, tissue cohorts and a luciferase assay identifies miR-183-3p as a candidate ESR1 3′-UTR-binding ...

MicroRNA Scars of Heart Failure Persist After LVAD Support in Ischemic Cardiomyopathy

A paired tissue study of 11 patients finds that microRNA patterns tied to apoptosis and fibrosis remain largely unchanged after ...

AI tool maps candidate microRNA sites on circular RNAs

The circMAC model predicted candidate microRNA-binding regions across complete circular RNA isoforms while preserving sequence continuity at back-splice junctions.

International observational study tests PANXEON for early pancreatic cancer