Review Highlights Epigenetic and Metabolic Remodeling in Pulmonary Arterial Hypertension
A scientific review details how disrupted metabolic pathways regulate epigenetic remodeling in pulmonary vascular cells during pulmonary arterial hypertension.
Tag: Metabolic regulation
Review Analyzes Olive Phenol Hydroxytyrosol Across Cellular Pathways and Clinical Trials
A systematic review examines the cellular mechanisms, pharmacokinetic limitations, and available clinical evidence for the olive oil compound hydroxytyrosol across ...
Yi Zhi Ren Fruit Shows Neuroprotective and Metabolic Effects in Preclinical Studies, But Human Evidence Remains Scarce
A new review finds that the traditional Chinese fruit Yi Zhi Ren shows broad neuroprotective and metabolic activity in cell ...
Scientists Launch First Dedicated Database for Monascus Fungi and Their Metabolites
Researchers have built FoodFungi, the first comprehensive database dedicated to the genus Monascus, integrating 17 species, 509 metabolites, and more ...
Electrical and Optical Properties Distinguish Adipose Tissue Depots and Offer a Promising Route to Monitoring Beiging
Researchers at the University of Oslo report that the passive electrical and optical properties of adipose tissue can distinguish between ...
Hidden RNA Molecules Emerge as Master Regulators of Type 2 Diabetes
A new review synthesizes a decade of evidence showing that long noncoding RNAs regulate insulin resistance, beta-cell failure and diabetic ...
Energy’s Hidden Role in Consciousness: A New Framework Puts Brain Metabolism in the Spotlight
A new Hypothesis and Theory article proposes that the brain's systems-level energetic organization may act as a biological constraint on ...
Excess cysteine releases iron, overwhelming mitochondria and killing cells
A CRISPR screen and laboratory experiments show that excess cysteine releases iron from ferritin, damages mitochondria and triggers cell death.
Epithelial and Mesenchymal Stem Cells Shape Mammary Gland Biology
A review integrates murine, human, and bovine evidence on epithelial and mesenchymal stem cells in the mammary gland, highlighting mTORC1-dependent ...
LPA₃ signaling and biological functions: from physiological regulation to disease-targeted therapy
A 2026 review summarizes LPA₃ signaling across tissues and diseases, identifies possible therapeutic applications, and frames selective antagonists, biased ligands ...
Starving the Sprouts: Cutting a Single Protein Slows Blinding Eye Disease in Mice
New mouse research shows that removing the protein lipocalin-2 from blood vessel cells curbs the destructive retinal vessel growth of ...
Toxic Sugar Metabolite Shapes the Biology of Lyme Disease Spirochetes
New research in PLOS Pathogens reveals that the Lyme disease spirochete actively produces the reactive metabolite methylglyoxal to modify its ...
Lipid Droplets: Dynamics and Organelle Interactions Explored
Lipid droplets (LDs) have traditionally been viewed primarily as energy storage depot, but recent studies have revolutionized our understanding of ...
AMPK: Key Player in Energy and Nutrient Sensing
The intricate choreography of cellular metabolism hinges upon the seamless integration of diverse signals conveying the status of energy reserves ...
LipoID Uncovers Lipid Droplet Interactions and Regulators
Lipid droplets (LDs) are gaining increasing attention in the world of cellular biology due to their fundamental role in metabolic ...
Testosterone: Key Metabolic Messenger Uncovered
Testosterone, a cornerstone of endocrinology first isolated and synthesized in the 1930s, has long been recognized as the quintessential male ...
Canagliflozin Controls Fat Cell Lipolysis Independently
In a groundbreaking study that may redefine our understanding of metabolic regulation and diabetes treatment, researchers have uncovered a novel ...
Autophagy Limits Obesity Fibrosis via Purine Signaling
In a groundbreaking study published in Nature Communications, researchers have uncovered a pivotal role for autophagy in moderating obesity-related fibrosis ...
Daily Fluctuations in Human Plasma Proteins Revealed
Recent advances in the field of proteomics have unveiled the complex dynamics of the human plasma proteome, a key player ...
