Age, Lactate and Procalcitonin Sharpen COPD Death Risk Score in Two-Cohort Study
An augmented DECAF score adding age, lactate and procalcitonin outperformed the original score for predicting 30-day mortality in COPD exacerbations ...
Tag: Mechanical ventilation
Study Finds No Long-Term Outcome Difference in Post-Intubation Stenosis
A retrospective cohort study finds that long-term clinical outcomes for post-intubation tracheal stenosis are comparable whether the condition is related ...
Respiratory Herpesvirus Reactivation Linked to Alveolar Inflammation in Critical Illness
Researchers evaluate how pulmonary herpesvirus reactivation defines localized inflammatory phenotypes and influences clinical outcomes in patients with persistent acute respiratory ...
Respiratory Viruses Do Not Worsen Outcomes in Ventilated Nosocomial Pneumonia
A matched case-control study reveals that respiratory virus detection does not significantly worsen mortality, duration of mechanical ventilation, or intensive ...
Expiratory Muscle Work Alters Regional Response to PEEP in Hypoxemic Patients
A secondary physiological analysis found that active expiratory muscle activity during high PEEP attenuates dorsal lung volume gains and increases ...
Machine Learning Predicts Extubation Failure in Critical COPD Emergency Resuscitation
An interpretable random forest model trained on early emergency resuscitation data accurately predicted extubation failure in mechanically ventilated patients with ...
Invasive Pulmonary Aspergillosis Struck Nearly 12% of ICU Patients in the COVID-19 Era, Global Meta-Analysis Finds
A systematic review of 56 studies covering 15,385 ICU patients found invasive pulmonary aspergillosis incidence of 11.9% and overall mortality ...
International Delphi Study Establishes Core Outcomes for Brain Injury Ventilation Trials
An international Delphi consensus study across 31 countries established a 13-outcome core set and a three-level hierarchical composite endpoint for ...
Biomedical engineering’s next test: proving value where patients actually live
A new journal section challenges biomedical engineers to prove their devices deliver real clinical outcomes for patients, from intensive care ...
Early Vulnerability, Not Ventilation Alone, Drives Pneumonia After Brain Injury
A narrative review proposes that severe traumatic brain injury compresses established pneumonia mechanisms into an early vulnerable window, explaining clustered ...
Chlorhexidine adds no benefit to oral-care bundles for preventing ventilator-associated pneumonia
A cluster-randomized crossover trial in six Indian medical intensive care units found that adding 0.12% chlorhexidine to a standardized oral-care ...
Dorsal Lung Ventilation Drop During Surgery Flags Postoperative Pulmonary Complications
A prospective cohort study of 91 laparoscopic colorectal cancer surgery patients found that a 14.5 percent or greater reduction in ...
Research report: Multimodal analgesic regimen is associated with earlier bowel recovery in infants undergoing liver transplantation: a cohort study
A retrospective cohort study of 82 infants found that a multimodal analgesia regimen combining sufentanil, esketamine, and dexmedetomidine was associated ...
Pneumonia-driven ARDS emerges as biologically distinct syndrome demanding tailored care
A narrative review argues that pneumonia-driven ARDS is a biologically distinct, heterogeneous form of respiratory failure in which pathogen burden, ...
RNA Sequencing Reveals Inflammatory Pathways Behind Ventilator-Induced Diaphragm Damage in Rats
Transcriptome sequencing of ventilated rat diaphragms identifies MAPK, PI3K-Akt, and Calcium signaling as inflammation-linked pathways associated with muscle fiber atrophy ...
Breathing by the numbers: bedside lung mechanics reshape ARDS ventilation
A new review argues that real-time measurements of respiratory mechanics can personalize ventilator settings in ARDS, though key strategies still ...
Optical fibre sensor inside tracheal tube cuff detects airway wall contact in bench tests
Bench tests show a tracheal tube with fibre Bragg grating sensors embedded in its cuff can detect contact with the ...
Ultrasound-guided tracheostomy proves safe option in COVID-19 ICU patients
A retrospective cohort study at a Croatian hospital found that ultrasound-guided percutaneous dilatation tracheostomy in 99 COVID-19 ICU patients produced ...
Music, Virtual Reality and Family Care Emerge as PICU Sedation Adjuncts
A narrative review finds that distraction, music, family-centered care and environmental modifications show promise as adjuncts to sedation in critically ...
Ventilator brand, not mode, drives electricity use in ICU bench study
A bench study of nine intensive care ventilators found that brand, not ventilation mode, was the dominant determinant of electricity ...
POPULAR NEWS
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Blood cell ratios run lower in asthma-COPD overlap than COPD, meta-analysis finds
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Online HIV Research Cohorts Uncover Widespread Participant Fraud and Deceptive Tactics
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Study Evaluates Infection Screening Markers Among Voluntary Blood Donors in Addis Ababa
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Hepatic Vulnerability Is Associated with Post-Hepatectomy Liver Failure and Major Morbidity After Curative-Intent Resection of Perihilar Cholangiocarcinoma