Tag: immunotherapy

A review finds that fungal compounds can suppress tumour growth, alter immunity and limit metastasis in skin-cancer models, but manufacturing, ...

A prespecified interim analysis of the phase 3 HARMONi-2 trial shows ivonescimab achieved median overall survival of 30.8 months versus ...

New research links the lipid-binding protein OSBPL3 to colorectal cancer progression, gut microbiota shifts, and immune microenvironment changes, with two ...

A case report describes a child with B-ALL who recovered from probable blinatumomab-associated lung injury and completed a monitored, dose-escalated ...

A new Oncotarget case report details how the WIN Consortium's international molecular tumor board evaluated investigational EGFR, MDM2, CDK4/6 and ...

A retrospective cohort study of 194 patients with esophageal squamous cell carcinoma found that postoperative pathological lymph node stage, rather ...

An exploratory multicenter biomarker analysis shows that pretreatment plasma lncRNA RIME, especially when combined with PD-L1, distinguishes patients with advanced ...

Updated Phase 3 DUO-E trial results presented at ESMO 2026 show that durvalumab plus olaparib after chemotherapy achieved a median ...

A review in the Journal of Ovarian Research surveys clinical trial evidence on CAR-T, TCR-T, TIL and NK cell therapies, ...

Microparticles made from red blood cells deliver haem to the nucleus of dendritic cells, activating a pathway that boosts cytotoxic ...

A scoping review of 38 studies maps the evidence for ultrasound-triggered microbubble and nanobubble platforms in breast cancer imaging, local ...

A multi-cohort re-analysis of melanoma transcriptomes and single-cell immune data links coordinated checkpoint-gene expression to longer overall survival, treatment-related immune ...

A study in Journal of Translational Medicine shows that the tumor protein stratifin stabilizes PAK1 and activates MYC-driven NECTIN2 expression, ...

A retrospective Chinese study of 102 elderly patients with inoperable esophageal squamous cell carcinoma found that a pretreatment absolute lymphocyte ...

The FDA granted accelerated approval for dostarlimab in adults with stage II or III locally advanced rectal cancer whose tumors ...

A 23-article collection reports advances in kidney cancer classification, prognosis and treatment while showing that prevention, early detection and prospective ...

An abstract summarizes in vitro evidence that sLTA enhanced NK-cell activity and sensitized HT-29 colon cancer cells to apoptosis in ...

A review finds evidence that ultraviolet-based phototherapy can modulate immune and inflammatory responses and may complement immunotherapy in several biomedical ...

A review finds that programmed cell death can promote immune evasion or antitumour immunity in oropharyngeal cancer depending on pathway ...

A published protocol describes a planned first-in-human trial of an investigational product: an autologous chimeric antigen receptor T-cell therapy designed ...