Tag: immunotherapy

New loop-structured CAR-T cells targeting CD38 and CD123 show enhanced activity against heterogeneous acute myeloid leukemia in preclinical models.

A review published in Discover Immunity synthesizes evidence on the immunological mechanisms and neuroinflammatory pathways driving amyotrophic lateral sclerosis alongside ...

A case report in Frontiers in Oncology describes a patient with rare intestinal hepatoid adenocarcinoma who achieved complete remission of ...

A review in Biological Research details how telomerase-targeted therapies, including imetelstat and peptide vaccines, are advancing cancer treatment by disrupting ...

Researchers have demonstrated that reprogramming cancer cells into dendritic cells promotes tertiary lymphoid structures that help coordinate antitumor immune responses ...

A systematic review evaluates how organoid coculture models reconstitute tumor microenvironments to improve preclinical drug screening and immunotherapy evaluation.

A computational analysis of public sequencing data predicts a private neoantigen repertoire and copy number driven cell-surface targets in malignant ...

A Virginia Tech researcher has received a five-year NIH award to develop a microneedle patch that could attract, reprogram and ...

A new study shows that tumor heterogeneity significantly impacts the success of STING and LTβR-mediated tertiary lymphoid structure induction in ...

A phase 2 trial found that adding immunotherapy to chemotherapy did not improve the primary efficacy endpoint in advanced ovarian ...

A Bayesian network meta-analysis reveals that class-level rankings for first-line HCC immunotherapy are confounded by trial population characteristics, rendering drug ...

A retrospective study in BMC Cancer found that adding camrelizumab to TACE and apatinib improved response and survival in elderly ...

A bibliometric analysis of more than 27,000 publications tracks the growth of cancer siRNA therapies, shifting delivery technologies, and persistent ...

A target-trial emulation involving 2,713 patients with allergic respiratory disease found that initiating sublingual immunotherapy was associated with reduced disease ...

Researchers developed a multiplexed immunoassay that measures immune checkpoint proteins on the surface of plasma extracellular vesicles and found generally ...

A study reveals that tumor ICAM1 is required for effective Vδ2 T cell immunotherapy in triple-negative breast cancer and can ...

Clinicians documented the rare concurrent emergence of rheumatoid arthritis and Sjögren's syndrome in a patient receiving nivolumab for recurrent gastric ...

A prospective multicenter cohort study evaluates whether plasma-derived extracellular vesicles can predict response to anti-PD-(L)1 therapies in patients with advanced ...

Researchers developed a four-gene panel that stratifies sepsis patients into distinct immunological endotypes associated with differential mortality risks under hydrocortisone ...

An ex vivo study shows tailored PEI-PLGA nanovaccines functionalized with poly(I:C) enhanced neoantigen-specific T-cell activation in cells from melanoma patients.