Tag: immunotherapy

A new review highlights the JAK/STAT signalling pathway as a potential link between SARS-CoV-2 infection, post-COVID autoimmune phenomena and the ...

Gladstone Institutes physician-scientists Melanie Ott and Alex Marson have been elected to the National Academy of Medicine in recognition of ...

A new study shows that cooperative signals from macrophages, stellate cells and cancer cells switch on the tumor-promoting protein CHI3L1 ...

A phase 3 trial shows sacituzumab tirumotecan significantly lowers the risk of cancer progression and death in women with recurrent ...

A study in Medical Oncology reports that the E3 ubiquitin ligase RNF152 is low in clear cell renal cell carcinoma, ...

A new review details how metabolites produced by Fusobacterium nucleatum drive periodontal inflammation, reprogram colorectal tumor metabolism and immunity, and ...

Phase 3 DeLLphi-305 results show that adding tarlatamab to durvalumab as first-line maintenance therapy extended median overall survival by more ...

A new review argues that natural killer cells in colorectal cancer liver metastasis form a heterogeneous, microenvironment-shaped spectrum of states ...

A case report in Oncotarget describes how an international molecular tumor board weighed treatment options for a 52-year-old woman with ...

Triple-negative breast cancer represents a particularly aggressive subtype of the disease, characterized by the absence of hormone receptors and HER2 ...

Phase 3 trial results presented at ESMO 2026 show that adding personalized mRNA vaccine intismeran to pembrolizumab reduces melanoma recurrence ...

An integrated transcriptomic and tissue-level study links an eight-gene risk score and the immune regulator RGS1 to survival in gastric ...

A retrospective multicenter study linked class III BRAF alterations in metastatic NSCLC to shorter overall survival and distinct co-mutation patterns ...

A three-day 2026 conference in Houston will examine emerging cancer therapeutics, targeted protein modulation, immunotherapies and artificial intelligence in drug ...

In a retrospective I3LUNG study of 2,396 patients, multimodal AI outperformed standard clinical biomarkers for survival-outcome prediction, and AI support ...

A Dana-Farber-led Immunity study shows that p53-mutant cancers can evade T-cell detection through several mechanisms, while laboratory ERAP1 inhibition restores ...

An observational study of more than 200 children and young people found that early response to blinatumomab and leukemia genetics ...

A single-patient case report documents delayed toxic epidermal necrolysis after six cycles of pembrolizumab and enfortumab vedotin for metastatic urothelial ...

A narrative review in Cancer Cell International outlines how artificial intelligence can integrate genomic, transcriptomic, imaging, and other multi-omics data ...

An editorial reviewing 15 studies finds that single-cell, spatial, metabolic, epigenetic and imaging methods expose cellular ecosystems associated with metastatic ...