Hydrogels That Time Antibiotics and Growth Factors Could Reshape Infected Bone Repair
A new review maps how hydrogels engineered to release antibiotics first and growth factors second could integrate infection control and ...
Tag: immunomodulation
Machine Learning Maps How Live and Heat-Killed Probiotics Shape Immune Responses
A single-donor laboratory study found live probiotic bacteria triggered far stronger cytokine responses than heat-killed preparations, yet the killed bacteria ...
Nanomaterials Converge on Endometriosis With Targeted Delivery, Immune Reprogramming and Ablation
A new review maps how lipid nanoparticles, polymeric carriers, nanomicelles, macrophage-targeted immunotherapy and nanoparticle-driven photothermal and magnetic ablation could shift ...
Mouse Studies Map the Broad Immunomodulatory Reach of Bacterial Lysates
A systematic review of 34 murine studies published from 2010 to 2025 finds bacterial lysates show consistent preclinical immunomodulatory effects ...
Tapeworm Protein Dampens Immune Alarm to Limit Heart Reperfusion Injury in Mice
In a mouse study, a recombinant Echinococcus granulosus protein shifted macrophages toward a repair-associated state by dampening the cGAS–STING pathway ...
Probiotics and pidotimod face scrutiny for residual immune activation in HIV
A 2026 mini-review finds that probiotics and pidotimod remain investigational for residual immune activation in treated HIV, with heterogeneous studies ...
Smart nanoplatforms aim to make sepsis therapy responsive to disease stage
A review finds that stimulus-responsive nanoparticles can detect pathological signals in sepsis models and release antimicrobial, anti-inflammatory and immune-regulating drugs ...
Sepsis Treatments Shift Toward Precision, Multi-System Pharmacology
An editorial reviewing 21 contributions argues that sepsis therapy is shifting from broad cytokine suppression toward phenotype- and timing-based treatments ...
Pentalinonsterol shows dual antileishmanial effects in preclinical evidence
A critical review finds that pentalinonsterol acts against Leishmania in experimental models while also altering several host-cell pathways, but its ...
Beyond cell transplants: The next frontier in mesenchymal stem/stromal cell therapy and regenerative medicine
The reframing of mesenchymal stem and stromal cells as regulatory hubs rather than building blocks represents more than a semantic ...
Nanogels and micelles tame doxorubicin’s inflammatory side effects in macrophages
Chemotherapy saves lives, but it can also leave chaos in its wake. One of the most widely used anticancer drugs, ...
Piezoelectric Materials Could Rewrite the Rules of Bone Infection Treatment
A new review examines how piezoelectric biomaterials that convert mechanical force into electrical signals could eradicate bacteria, recalibrate the immune ...
Plant Vesicles Turn Herbal Cancer Drugs Into Precision Weapons
A new review argues that plant-derived extracellular vesicles can both deliver and amplify the anticancer power of plant natural products, ...
Fish-Skin Hydrogel Patch 3D-Printed to Heal Stubborn Diabetic Wounds
Researchers 3D-printed a composite hydrogel patch from tilapia and carp skin extracellular matrix that promoted wound closure, reduced inflammation, and ...
Molecular Hydrogen Emerges as a Versatile Adjuvant in Cancer Therapy
A new review in Frontiers in Chemical Biology maps how molecular hydrogen reprograms oncogenic signaling, epigenetics, mitochondrial stress, and antitumor ...
When a Fever Attacks the Brain and Heart: A Rare Childhood Syndrome Challenges Doctors
A case report from Tehran describes a four-year-old girl with acute necrotizing encephalopathy of childhood complicated by fulminant myocarditis, highlighting ...
Why Beta-Lactams and Macrolides May Work Better Together Than Alone
A comprehensive review finds that beta-lactam–macrolide combination therapy shows its clearest benefit in severe community-acquired pneumonia, while most proposed synergy ...
Maitake Mushroom Science Matures: Global Analysis Maps Four Decades of Bioactivity Research
A new scientometric analysis of 605 studies maps four decades of maitake mushroom research, revealing a maturing field centered on ...
GMP-Compliant Platform Turns Wharton’s Jelly Stem Cells Into Clinical-Grade Extracellular Vesicles
Researchers have built and validated a GMP-compliant, semi-automated manufacturing platform that produces clinical-grade extracellular vesicles from Wharton's jelly-derived mesenchymal stromal ...
Liver Flukes Deploy Tiny Molecular Messengers to Disarm the Host Immune System
A new review synthesizes how extracellular vesicles released by Fasciola liver flukes manipulate host immunity and could guide novel vaccines ...
