Reprogramming the Immune System: A New Toolbox for Healing Chronic Wounds
A new review outlines how immunomodulation and immunoengineering, from extracellular vesicles and stem cells to smart theranostic dressings, could reset ...
Tag: immunomodulation
Fat Tissue’s Hidden Cocktail May Rewire Inflamed Immune Cells, Review Finds
A new review proposes that the secretome of freshly isolated adipose-derived Stromal Vascular Fraction can dampen NF-κB signaling and reprogram ...
Trehalose, the Gut Microbiome, and a New Lead in Multiple Sclerosis Research
A new review suggests that the natural sugar trehalose may influence multiple sclerosis by inducing autophagy, reducing inflammation, and reshaping ...
Molecular Cage Supercharges Blood-Thinner Absorption and Calms Inflammation in Mice
A cucurbituril host–guest formulation of ticagrelor boosts solubility, doubles systemic exposure, and shifts macrophages toward an anti-inflammatory state in preclinical ...
High-Dose Vitamin C Reprograms Immune Cells to Boost Pancreatic Cancer Immunotherapy
New research shows that high-dose vitamin C activates the JAK2-STAT1 pathway to drive macrophages toward an anti-tumor M1 state, enhancing ...
Dead Probiotic Cells Show Promise for Healing Infected Burn Wounds in Mice
A new mouse study shows that non-viable probiotic cells, or paraprobiotics, can suppress bacterial virulence factors and shift infected burn ...
Ginseng Compound Rb1 Starves Pancreatic Tumors by Turning Off Their Macrophage Allies
A ginseng-derived saponin suppresses pancreatic cancer in preclinical models by blocking the PI3K-AKT pathway and preventing macrophages from adopting a ...
Tiny Vesicles Reveal How Toxoplasma gondii Quietly Rewires Its Host
A new review argues that extracellular vesicles released by Toxoplasma gondii and infected host cells act as strategic molecular messengers ...
Common Arthritis Drug Fails to Ease Severe Leprosy Complication in Global Trial
An international randomised trial found that adding weekly oral methotrexate to prednisolone did not reduce flares or steroid requirements in ...
Common Antibiotic Calms Children’s Wheezing by Rewriting Inflammatory Memory in Lung Immune Cells
A new study shows azithromycin eases post-inflammatory wheezing in children by inhibiting SETD1B-driven H3K4me3 methylation and rebalancing macrophage polarization in ...
Stem Cell Vesicles Quiet Inflammatory Immune Signals in Osteoarthritis Patients
A new in vitro study reports that mesenchymal stem cell-derived extracellular vesicles reduced Th1 cell frequency, STAT1 expression, and inflammatory ...
Stem Cells Reshape the Gut Microbiome, but a Blood Pressure Cure Remains Elusive
A systematic review of 31 preclinical studies finds that mesenchymal stem cell therapy can modulate gut microbiota across multiple disease ...
Ancient Chinese Herb Yields a Polysaccharide That Kills Staph and Calms Runaway Inflammation
A fructan polysaccharide from the traditional Chinese herb Polygonatum kingianum killed Staphylococcus aureus, eradicated mature biofilms, and restored balanced immune ...
Deer Antler Velvet Draws Scientific Scrutiny as Regenerative Super-Ingredient
A new comprehensive review finds that deer antler velvet is packed with growth factors and bioactive compounds, but warns that ...
Assessing Wharton’s Jelly Biologics: Composition and Impact
In recent years, the field of regenerative medicine has made significant strides, particularly in the utilization of biologics derived from ...
Extracellular Vesicles: Tumor Immune Microenvironment Influence
Extracellular vesicles (EVs) are increasingly recognized as pivotal players in intercellular communication, particularly concerning their significant impacts on the tumor ...
Resveratrol Targets HLA-A in Diabetic Retinopathy Treatment
In a groundbreaking study led by a team of researchers including Lin, J., Liang, F., and Liu, Y., the complex ...
Mosquito Salivary Sialokinin Eases Chikungunya Inflammation
In a groundbreaking study that could reshape our understanding of mosquito-borne diseases, researchers have unveiled a surprising role played by ...
