Tag: Immunohistochemistry

An analysis of 81 Ethiopian breast cancer tissue samples associated higher immune-cell and PD-L1 measures with non-luminal subtypes and grade ...

Nepal retrospective study characterizes 51 ALK- or ROS1-positive tumors

A Nepal single-centre retrospective study characterized 51 ALK- or ROS1-positive cases, including 49 non-small cell lung cancers and two inflammatory ...

Association between CISD2 expression and clinicopathological features and prognosis in gastric cancer: a systematic review, meta-analysis, and database validation

A three-study meta-analysis and an independent database analysis suggest that CISD2 expression may be associated with gastric cancer invasion and ...

HCMV markers linked to aggressive glioma features and shorter survival

A retrospective study of 221 glioma specimens associated HCMV IE1 protein and UL123 DNA with aggressive tumor features and shorter ...

Case report tracks aggressive pulmonary choriocarcinoma with brain metastases

A case report and small literature review found that serial β-HCG tracked disease progression in aggressive pulmonary choriocarcinoma, while checkpoint-inhibitor ...

Rare Painless Tumor on a Woman’s Nose Turns Out to Be Something Far Stranger

A 63-year-old woman's painless nasal lump, clinically suspected to be a lipoma, was revealed after excision to be a glomangiomyoma ...

Persistent nail separation may hide a rare melanoma

A 74-year-old man's year-long thumbnail detachment was misdiagnosed as a fungal infection before biopsy revealed subungual amelanotic melanoma, a rare ...

Inflammatory NF-κB Signaling Comes Alive in the Septa of Newborns with Intestinal Atresia

A study of human septal tissue from infants with type I intestinal atresia reveals markedly increased expression of NF-κB pathway ...

Two BCL-2 Gene Variants Linked to Protein Levels and Aggressive Bladder Cancer

Brazilian researchers have found that a BCL-2 promoter variant influences protein expression in bladder tumors while a specific haplotype triples ...

Lung Cancer That Hid in the Uterus: Rare Metastasis Fooled Doctors

A 77-year-old woman's uterine tumor turned out to be metastatic lung adenocarcinoma, a case highlighting how immunohistochemistry and genomic sequencing ...

Rare Tumor Hiding Inside a Salivary Gland Lymph Node Challenges Pathologists

A 30-year-old patient's parotid mass turned out to be only the second reported epithelioid schwannoma arising within an intraparotid lymph ...

Vimentin Emerges as a Powerful Prognostic Marker in Triple-Negative Breast Cancer

A retrospective cohort study from Indonesia's national referral hospital links vimentin expression to dramatically shorter survival in triple-negative breast cancer ...

CD117 Staining for GIST: UK EQA Data Reveal Significant Antibody Performance Differences

Analysis of 2,656 submissions across 20 UK NEQAS ICC & ISH assessment runs between May 2020 and May 2025 shows ...

Thirteen Years Cancer-Free, Then a Seizure: Rare Brain Metastasis Stuns Doctors

A 58-year-old man developed a solitary brain metastasis from gastroesophageal junction adenocarcinoma thirteen years after curative treatment, a case that ...

Rare Skin Nodules Reveal Hidden Lymphoma in Unusual Case Report

A rare case report documents angioimmunoblastic T-cell lymphoma presenting as multiple painless subcutaneous nodules, expanding the recognized cutaneous spectrum of ...

Two PET scans may outsmart a single biopsy in predicting aggressive neuroendocrine cancer outcomes

A new study shows that discordant lesions on dual-tracer FDG and FAPI PET/CT strongly predict shorter progression-free survival in aggressive ...

Benign-Looking Ultrasound Features May Hint at Aggressive Triple-Negative Breast Cancer

New research from Türkiye finds that triple-negative breast cancers can present with deceptively benign-looking ultrasound features, challenging conventional radiological assumptions ...

TRK Protein Staining in Childhood Rhabdomyosarcoma Flags Aggressive Tumors but Misses the Gene Fusions That Matter