Probiotic Plus HIIT Improves Memory in Rats
A study in Behavioral and Brain Functions found that combining the probiotic Lactobacillus rhamnosus GG with high-intensity interval training improved ...
Tag: high-fat diet
High-Fat Diet Obesity Disrupts MYC-PPIL1 Network in Male Infertility
A new study reveals that high-fat diet-induced obesity disrupts the MYC-PPIL1 network, leading to reduced sperm motility and increased oxidative ...
NAC Modifies Bladder Changes in High-Fat Diet Study
A study in BMC Urology finds that N-acetylcysteine partially reduces oxidative and inflammatory changes in bladder dysfunction associated with high-fat ...
Two Enzymes Team Up to Drive Fat Cell Formation and Obesity
Researchers found that the enzymes USP25 and USP28 work together to stabilize key fat-forming transcription factors, and blocking both simultaneously ...
Prenatal Nutrition Dominates Autophagic Programming in Growth-Restricted Rat Offspring
A rat study reveals that fetal growth restriction programs long-term autophagic dysfunction independently of post-weaning high-fat diet exposure.
Male mice pay a heavier metabolic price for a fatty diet
A 40-week mouse study found that males on a high-fat, high-cholesterol diet developed more severe muscle atrophy than females, linked ...
Transcriptomic Study Links TAZ to Gut Immune Imbalance in Diabetes
An integrative transcriptomic analysis identifies TAZ as a conserved candidate associated with intestinal Th17/Treg immune imbalance in mouse models of ...
Macrophage TRPV1 Loss Worsens Diet-Driven Colitis and Gut Fibrosis in Mice
Deleting Trpv1 in myeloid cells worsened inflammation, fibrosis and barrier dysfunction in mice with high-fat diet-exacerbated chronic colitis, via a ...
Boiled and Finely Ground Balsam Apple Leaf Powder Lowers Cholesterol in Rats
A rat study found that cooking and sieving Momordica balsamina leaf powder into fine fractions improved its extractable polyphenol content ...
Fermented Potato Peel Extract Eased Fatty Liver Disease in Obese Rats
A study in obese rats found that potato peel extract fermented with Rhizopus oryzae reduced hepatic fat accumulation, improved lipid ...
Swim Exercise and Scent Leaf Extract Reverse Cardiometabolic Changes in Obese Rats
A 22-week rat study found that swimming exercise and Ocimum gratissimum leaf extract, alone or combined, significantly reversed obesity, high ...
High-Fat Diet Reshapes the Mouse Gut Microbiome in Distinct, Timed Phases
A dense 70-day mouse study shows a high-fat diet restructures gut microbiota in distinct phases, with Duncaniella depletion preceding weight ...
Obese pigs stay metabolically healthy as fat and liver tissue diverge in gene response
Ossabaw pigs fed a high-fat, high-fructose diet gained weight but showed normal metabolic blood markers, with distinct transcriptional responses in ...
Gut Microbe Metabolite May Explain How Butyrate Protects the High-Fat-Diet Colon
In diet-induced obese mice, dietary butyrate improved colonic barrier markers, and fecal microbiota transfer experiments linked the benefit to Bacteroides ...
Stevioside Boosts Muscle Glucose Uptake in Prediabetic Mice Through a Newly Mapped Signaling Axis
A new mouse study shows that the natural sweetener stevioside improved glucose metabolism in prediabetic animals by activating the JAK2/STAT3/IL6ra ...
Gut microbe metabolite worsens PCOS-like ovarian dysfunction under metabolic stress
A study links the gut bacterium Bacteroides fragilis and its metabolite indole-3-acetic acid to PCOS-like ovarian abnormalities that emerge only ...
Obesity May Harm Sperm Motility Through a STAT3/MTND4 Mitochondrial Pathway in Mice
A mouse and cell study reports that STAT3 transcriptionally activates MTND4, driving ROS production and mitochondrial dysfunction linked to obesity-related ...
Magnolol curbs fatty liver damage in mice by suppressing MOGAT1 enzyme
A new mouse study reports that magnolol protects the liver from high-fat diet injury by suppressing the triglyceride-synthesis enzyme MOGAT1 ...
Seaweed fiber fucoidan reshapes gut microbiota and protects mice from fatty liver disease
A 14-week mouse study found that fucoidan, a sulfated polysaccharide from brown seaweed, attenuated high-fat-diet-induced fatty liver disease in association ...
Fatty Diet Leaves Lasting Senescence-Like Scars in the Liver’s Regenerative Cells
A rat study finds that chronic high-fat diet feeding leaves liver organoid-forming regenerative cells locked in a senescence-like state with ...
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