Semaglutide linked to modestly lower cerebrovascular risk in meta-analysis of 27 trials
A meta-analysis of 27 randomized trials found semaglutide was associated with a modestly reduced risk of overall cerebrovascular events in ...
Tag: GLP-1 receptor agonist
Tirzepatide goes under the PET scanner in new alcohol use disorder trial protocol
A published protocol details a randomized, double-blind crossover PET/MRI trial that will test whether tirzepatide modulates striatal dopamine signaling and ...
Weekly IcoSema injection cuts weight and blood pressure in type 2 diabetes
A meta-analysis of two phase 3 trials found once-weekly IcoSema reduced body weight by 6.1 kilograms and improved blood pressure ...
Dulaglutide modestly raises amylase and lipase in meta-analysis of diabetes trials
A meta-analysis of randomized trials found dulaglutide raised serum amylase and lipase modestly in overweight and obese patients with type ...
Liraglutide speeds diabetic foot ulcer healing in randomized trial
A randomized placebo-controlled trial of 105 older patients found that liraglutide shortened diabetic foot ulcer healing time and reduced circulating ...
Can Genes and Gut Microbes Predict Who Responds to Semaglutide for Liver Disease?
A new review builds an evidence-tiered framework for predicting GLP-1 therapy response in fatty liver disease using host genotype and ...
Tirzepatide in German Practice: Most Patients Start After GLP-1 Drugs or Insulin
A retrospective analysis of German office-based medical records found that most adults with type 2 diabetes started tirzepatide after prior ...
Liraglutide regulate osteogenesis-resorption via macrophage under compressive stress
A new cell study reports that liraglutide suppresses pressure-induced osteoclast differentiation and inflammation in macrophages while indirectly promoting osteoblast marker ...
CagriSema Shows Strong Dose-Specific Benefits for Type 2 Diabetes in Landmark Meta-Analysis
A new meta-analysis of six randomized controlled trials shows CagriSema significantly lowers HbA1c, body weight, and blood pressure in type ...
Stopping or Continuing GLP-1 Drugs Before Thyroid Surgery? A New Study Weighs In
A large target trial emulation found that continuing GLP-1 receptor agonists before thyroidectomy in adults with type 2 diabetes was ...
Tirzepatide Outperforms Semaglutide on Weight and Metabolic Health in New Comparison
An indirect treatment comparison of the SURMOUNT-1 and STEP 1 trials finds tirzepatide 10 and 15 mg delivers greater weight ...
Semaglutide Shifts Inflammation Blood Markers in Diabetes, With a Twist for Eye Disease
A retrospective study of 99 patients in Saudi Arabia found that semaglutide significantly altered systemic inflammation index ratios in type ...
Higher Dose of Oral Weight-Loss Pill Orforglipron Delivers Greater Results, Meta-Analysis Finds
A new meta-analysis of six randomized controlled trials finds that the 36 mg maintenance dose of the oral GLP-1 agonist ...
Oral Semaglutide Significantly Decreases Incidence of Heart Attacks and Strokes in Type 2 Diabetes Patients
In recent years, the therapeutic landscape for type 2 diabetes has witnessed groundbreaking advancements, particularly with the introduction of medications ...
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