Tag: Glioblastoma

A review describes how reciprocal crosstalk between the IL-6/STAT3 and purinergic signaling pathways drives chronic inflammation, immune suppression, and therapy ...

A comparative study reveals that temozolomide efficacy in murine glioblastoma models depends more on tumour antigenicity and microenvironmental immune context ...

A newly published editorial collection outlines computational breakthroughs developed by women researchers across metagenomics, quorum sensing, disease databases, and vaccine ...

A retrospective study demonstrates that electron density imaging from dual-energy CT can visualize high-grade gliomas similarly to contrast-enhanced MRI, offering ...

Researchers found that the protein DJ-1 promotes glioblastoma progression through the UBA52-mediated NF-κB signaling pathway in cell and mouse models.

A systematic review and meta-analysis of 14 studies encompassing 4,594 glioblastoma patients established a pooled median post-resection survival time of ...

A systematic review found no statistically significant correlation between preclinical rodent xenograft efficacy endpoints and phase II trial outcomes in ...

A computational framework named FOCUS paired with a support vector machine classified glioma IDH mutation status with 0.902 accuracy in ...

A review in Cellular & Molecular Biology Letters examines how ADAR-mediated RNA editing dysregulation contributes to pathogenesis in various central ...

A scientific review evaluates evidence on how cytomegalovirus may influence cancer stem cells and therapy resistance while noting that tumor ...

A review analyzes how glioblastoma stem cells and the perivascular niche remodel the blood-brain barrier into a persistent obstacle to ...

A scientific review outlines how copper-induced mitochondrial proteotoxicity could trigger innate immune sensing to counteract immunosuppressive microenvironments in glioblastoma.

Silencing HLA-DMA curbs glioblastoma cell malignancy and remodels tumor macrophages while enhancing anti-PD-1 immunotherapy efficacy in preclinical models.

A narrative review synthesises the cellular mechanisms, genetic engineering approaches, preclinical models, and clinical translation barriers of oncolytic virotherapy across ...

A multicenter study identified CDKN2A/B deletion, MET amplification, and PIK3R1 mutation as independent genomic markers of poor prognosis in IDH-wildtype ...

Researchers mapping DNA methylation across MGMT regulatory elements identified CpG-specific patterns in glioblastoma and melanoma brain metastases.

Cleveland Clinic research published in Cancer Cell shows that overactive platelets in glioblastoma patients slow cancer-fighting T cells, with blocking ...

Published in Cancer Nanotechnology in June 2026, the study details the development of a chelating agent-driven synthesis method for zinc ...

A histopathology-validated study demonstrates that FET PET detects non-contrast-enhancing glioblastoma with substantially higher sensitivity than contrast-enhanced MRI across tissue samples ...

New research identifies how TRIM24 and CDKN2A deletion drive glioma by reprogramming mevalonate metabolism, offering a potential dual-targeting therapeutic strategy.