Tag: Gene regulation

Researchers identified highly focused transcription factor binding sites in human cells, revealing that these narrow regions are essential for maintaining ...

Structural analyses using cryogenic electron microscopy reveal how the versatile oncoprotein DEK binds nucleosomes, bends linker DNA, and coordinates histone ...

A new genomic dataset provides muscle-specific CUT&Tag chromatin occupancy profiles for the transcription factor UNC-130 in Caenorhabditis elegans.

Researchers identified specific activator binding domains in yeast chromatin remodelling complexes SWI/SNF, RSC, and INO80, revealing distinct functional requirements for ...

Researchers identified five regulatory hub genes governing flavonol glycoside synthesis across extreme Epimedium chemotypes using transcriptomics and co-expression network analysis.

Researchers have discovered that reducing HOXD13 expression in prostate cancer cells hampers apoptosis and stimulates aggressive behavior through the MDM2 ...

A scientific review details how long non-coding RNAs regulate ion channels, neuroinflammation, and neural circuits across the nervous system to ...

A new study reveals that the host cell type significantly influences the epigenetic and transcriptomic profiles of Toxoplasma gondii, with ...

Lab-grown brain organoids from humans, chimpanzees and gorillas reveal nearly 600 genetic switches that are more active in human neural ...

A scientific review highlights how computational linguistics, statistical laws, and formal grammars help decode regulatory patterns across noncoding genomic sequences.

Integrated small RNA and transcriptome sequencing of Gnetum montanum identified 550 microRNAs and hundreds of sex-biased regulatory pairs linked to ...

A new study identifies lncRNAs LINC00504 and LINC00520 as key regulators of the balance between proliferative and invasive states in ...

Researchers mapped the complete genome and transcriptome of Rhodococcus aetherivorans L13, demonstrating how the bacterium slashes respiratory activity and repurposes ...

Deleting the Tcra enhancer revealed that it selectively regulates two distant genes across a TAD boundary while leaving closer neighboring ...

A comprehensive review details technological breakthroughs in epigenome editing platforms and highlights emerging in vivo strategies for disease modeling and ...

Researchers identified gene regulatory proteins TET2 and TP63 as novel factors governing the expression of the human D-amino acid oxidase ...

Researchers have discovered a regulatory DNA enhancer switch inside the ZBTB16 gene that enables the androgen receptor to suppress cell ...

A review in Clinical Epigenetics outlines experimental considerations and unresolved challenges for designing CRISPR-dCas9 epigenetic editing studies.

A new review outlines how CRISPR-based tools are being used to modify stress-responsive genes in rice and what still limits ...

A single-cell and spatial atlas of 12 glioblastoma tumours shows that cancer cells progress through the same ordered sequence of ...