Tag: Functional genomics

A new Python package called PoolParty streamlines the design of DNA sequence libraries for high-throughput biological experiments by using directed ...

A new multi-task adversarial autoencoder framework generates functional genomic sequences that preserve biophysical properties and emergent biological structure, outperforming standard ...

A hidden 137-kilobase inverted duplication linked to a T-DNA insertion, not the intended gene knockouts, explains the severe light-dependent growth ...

A conference synthesis report in BMC Proceedings outlines African priorities for precision oncology, from genomic infrastructure and cancer registries to ...

A new review argues that oral biofilm disease is driven by spatial architecture, matrix chemistry and metabolism rather than microbial ...

A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant ...

Researchers generated eyeless F0 CRISPR-Cas9 pax6 mutants in the slipper limpet Crepidula fornicata using a de novo transcriptome instead of ...

A new CRISPR-Cas9 barcoded library, BarMix, profiles 262 diverse yeast strains against 33 compounds and reveals 281 chemogenomic interactions.

A sweeping editorial on a 2024–2025 research collection describes how long-read sequencing, newborn screening, population genomics, and functional studies are ...

A systematic bibliometric analysis of 25 years of Ficus literature shows that only about 11.3 percent of publications address genomic ...

A direct-shoot regeneration protocol achieved 91.67% regeneration in sugar beet leaf explants and produced molecularly verified transgenic plants, 70% of ...

A transcriptomic study of Euonymus japonicus ‘Beihaidao’ generated 50,741 non-redundant transcript sequences and identified 36,941 SSR loci, while 16 selected ...

A white birch study identified 56 deubiquitinase genes and found experimental evidence that BpUBP3 contributes to pollen germination and pollen-tube ...

An engineered Rhizobium rhizogenes strain called AS109 enables efficient transient gene expression across diverse dicot crop species, opening rapid functional ...

A new BMC Genomics study identifies the first validated stable internal reference genes for accurate RT-qPCR gene expression analysis in ...

Researchers used untargeted exometabolomics to reveal that three lactic acid bacteria strains isolated from nipa sap, an indigenous tuber and ...

A Nature Neuroscience commentary highlights new evidence that genetic variants within Alu transposable elements help shape the size and structure ...

A new web-based platform called TurbOmics lets researchers integrate metabolomics, proteomics, and transcriptomics data using advanced statistical methods without any ...

A large-scale re-annotation of the Aspergillus fumigatus genome reveals that many presumed pathogen-specific genes are actually long non-coding RNAs, two ...

A new transposon-insertion sequencing method called HIDEN-SEQ systematically maps gene essentiality in bacteriophages and uncovers previously unknown antidefence factors.