A comprehensive scientific review outlines how spatial multi-omics technologies connect tissue coordinates, metabolic gradients, and cellular microenvironments to uncover the ...
An integrated single-cell transcriptomic atlas across development reveals progressive vascular niche maturation and demonstrates that blocking midkine enhances hematopoietic stem ...
An integrative multi-omics analysis links higher FADS3 expression to increased hepatocellular carcinoma risk, tumor-stromal crosstalk with cancer-associated fibroblasts, and adverse ...
A new study uses single-cell RNA sequencing to explore the tumor microenvironment in NF2-related and sporadic vestibular schwannomas, identifying endothelial ...
A study integrating spatial transcriptomics, single-cell RNA sequencing and a 27-patient clinical cohort links peritumoral tertiary lymphoid structures and high ...
Single-cell RNA sequencing identified three mTOR-associated microglial populations in tuberous sclerosis complex and focal cortical dysplasia type II, with disease-specific ...
An integrative analysis of human NOA transcriptomic data and a Utf1 conditional knockout mouse model identifies ACTRT2 and AKAP4 as ...
An integrative RNA sequencing and machine learning study identified a seven-gene signature and key liver cell subpopulations associated with advanced ...
A new single-cell RNA sequencing study maps how topical imiquimod remodels splenic immune cells in a lupus-like mouse model, revealing ...
An integrated single-cell and spatial transcriptomics study finds CXCR4 concentrated in dermal immune cells of psoriatic skin and identifies a ...
A single-cell atlas of healthy and COPD lung tissue identifies an HSPA1B-positive inflammatory monocyte state whose transcriptional program is associated ...
A study by Runqi Wang, Zhengran Li, Jing Wei, Jiajia Wang, Xiyue Liu Tao, Danjie Zhang, Ruiyan Kong, Xuejing Ren, ...
A single-cell RNA sequencing atlas of biliary atresia livers reveals expanded pro-inflammatory neutrophil subsets, activated cytotoxic lymphocytes, and injured endothelial ...
Single-cell RNA sequencing of hepatocellular carcinoma reveals that MRC1-positive macrophages, endothelial capillarization, and strengthened PTPRM signaling define the tumor ecosystem ...
A spatial transcriptomics study of fatal COVID-19 lungs reveals progressive loss of endothelial and immune cells, explosive peribronchial fibroblast expansion, ...
A new single-cell atlas of more than 500,000 cells shows that viral, bacterial, fungal and parasitic infections each leave distinct ...
A new Nature Reviews Molecular Cell Biology review unifies the rapidly expanding family of large extracellular vesicles, from apoptotic bodies ...
In the intricate development of an embryo, one organ stands out for its life-sustaining importance: the heart. New research published ...
