Oncotarget: MEK inhibitors relevant to SARS-CoV-2 infection
The @Oncotarget authors show a drug class-effect with MEKi to stimulate NK cells, inhibit inflammatory cytokines and block host-factors for ...
Tag: Carcinogens
Oncotarget: Targeting engineered cytokine with interleukin to the neovasculature of tumors
"The results suggest that this product, or similar fusion proteins featuring an N-terminal fusion in the diabody format, may deserve ...
Oncotarget: MEK is a promising target in the basal subtype of bladder cancer
"The @Oncotarget authors demonstrate that MEK inhibitors are a promising targeted therapy for the basal subtype of bladder cancer, and ...
Commuters are inhaling unacceptably high levels of carcinogens
Twenty minutes or longer in the car also raises risk of birth defectsCredit: Stan Lim/UCR A new study finds that ...
Antitumoral effects of LXR activation
Macrophages that boost tumor growthCredit: UNIVERSITY OF BARCELONA Tumor cells are able to avoid the attack of the immune system ...
Green tea compound aids p53, ‘guardian of the genome’ and tumor suppressor
Research offers new lead for cancer drug discoveryCredit: Rensselaer Polytechnic Institute TROY, N.Y. -- An antioxidant found in green tea ...
Oncotarget: Combination of copanlisib with cetuximab improves tumor response
"These data support further investigation of PI3K inhibition in HNSCC and suggests gene expression patterns associated with PI3K signaling"Credit: Correspondence ...
Oncotarget: Evaluation of cancer-derived myocardial impairments using a mouse model
'The established mouse cachexia model can therefore be considered useful for analyzing cancer-derived myocardial damage'Credit: Correspondence to - Yi Luo ...
Oncotarget: Melatonin increases overall survival of prostate cancer patients
'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown'Credit: Correspondence ...
Samara Polytech scientists proved the anti-cancer properties of a number of plant extracts
Extracts from black chokeberry, raspberry and fireweed have a special anti-carcinogenic and antioxidant effectCredit: @SamaraPolytech Samara Polytech chemists investigated the ...
Researchers studying stress, cancer risk and reproductive toxicity in women firefighters
Credit: University of Arizona/Kris Hanning Researchers at the University of Arizona Health Sciences are undertaking a study to better understand ...
Oncotarget: The goal of geroscience is life extension
Dr. Mikhail V. Blagosklonny from The Roswell Park Cancer Institute said, 'Although we do not know everything about aging, we ...
Significant cancer rates in California sea lions has major human health implications
Credit: Bill Hunnewell © The Marine Mammal Center Scientists at The Marine Mammal Center - the world's largest marine mammal ...
Oncotarget: The pro-apoptotic actions of 2-methoxyestradiol against ovarian cancer
The objective of this Oncotarget study was to elucidate the molecular mechanism of actions of 2MeOE2, a known microtubule disrupting ...