Tag: cancer metabolism

A review links obesity with varied lymphoma risks, biological changes and treatment outcomes while emphasizing that clinical findings remain heterogeneous ...

A peer-reviewed review examines protein acylation as a link among cancer metabolism, tumor plasticity, therapeutic resistance and proposed biomarker-guided treatment ...

Preclinical experiments show that METTL14 stabilizes FDX1 RNA through m6A methylation, promoting cuproptosis and suppressing clear cell renal cell carcinoma ...

A 2026 review describes altered amino acid transporters as potential metabolic vulnerabilities in hepatocellular carcinoma while identifying heterogeneity, redundancy, toxicity ...

A 2026 review links lactate-driven protein lactylation to glioblastoma growth, stemness, immune escape and treatment resistance in preclinical models, while ...

Human tissue associations and cell experiments link NUAK1 and NUAK2 to colorectal cancer growth, migration and metabolic reprogramming through AMPK ...

A plant-derived sterol called stigmasterol sabotages the metabolic machinery of glioblastoma cells by impairing mitochondrial function and increasing oxidative stress, ...

A new review argues that lung tumours run an integrated, adaptable metabolic network rather than isolated pathways, explaining growth under ...

Weill Cornell Medicine's Dr. Samie Jaffrey has received a five-year, $5.5 million NIH Director's Transformative Research Award to map how ...

A new computational framework links the metabolic enzyme NNMT to coordinated platelet, neutrophil, and immune exhaustion programs in circulating tumor ...

New research reveals that NEAT1-built nuclear structures called paraspeckles determine both the identity of pancreatic cancer cells and their resistance ...

A short isoform of the BRD4 protein helps gastric cancer cells resist ferroptotic cell death by sustaining glutathione production, thereby ...

TRIP13 protects LDHA from FBXW7-mediated degradation, sustaining a lactate-driven antioxidant program that helps colorectal cancer cells adapt to hypoxia and ...

A new review in the Chinese Medical Journal maps how epigenetic modifications and metabolic reprogramming fuel each other in hepatocellular ...

A new hypothesis proposes that chronic metabolic dysregulation epigenetically primes apoptosis-resistant cancer clones years before diagnosis, reframing treatment resistance as ...

A new review argues that cancer cells toggle between glycolysis and mitochondrial respiration in hybrid metabolic states, and that mapping ...

A new systems-level study in 3D lung adenocarcinoma models shows that nutrient availability drives tumour cells into two distinct mitochondrial ...

A new study finds that dynamic changes in blood lipid levels during chemotherapy can predict with high accuracy which luminal ...

Researchers report that oncogenic KRAS reprograms adenosine metabolism through NT5E upregulation and ADA suppression, creating an immunosuppressive tumor microenvironment that ...

A new meta-analysis of 25 studies finds that oral cancer patients show significantly lower total cholesterol, triglycerides, HDL, LDL, and ...