Metabolic Enzyme and Protein Lactylation Markers Signal Laryngeal Cancer Progression
A clinical cohort study demonstrates that elevated levels of LDHA, Pan-Kla, and H3K18la correlate with advanced disease and poorer survival ...
A clinical cohort study demonstrates that elevated levels of LDHA, Pan-Kla, and H3K18la correlate with advanced disease and poorer survival ...
Researchers have established an accessible laser capture microdissection workflow that enables deep spatial proteomic profiling from minute archival formalin-fixed tissue ...
A new review consolidates evidence that the secreted protein DKK1 acts through multiple signaling routes and is associated with poor ...
A new review maps how isothermal amplification combined with engineered nanomaterials is enabling ultrasensitive, portable detection of cancer-related nucleic acids ...
A systematic review of 25 studies finds optical fiber biosensors can detect cancer biomarkers down to attomolar levels, but most ...
A narrative review links heat shock proteins to gastric cancer invasiveness, resistance and immune modulation, but finds that most therapeutic ...
A review finds that HOTAIR links chromatin remodeling, tumor progression, metabolic adaptation and treatment resistance through functions that vary by ...
A 23-article collection reports advances in kidney cancer classification, prognosis and treatment while showing that prevention, early detection and prospective ...
Eleven studies using machine learning, single-cell profiling, imaging, liquid biopsy and clinical data identify candidate cancer biomarkers, but retrospective designs ...
A 2026 review identifies multiple mechanisms through which circular RNAs regulate Hippo signaling and summarizes evidence linking them to cancer ...
A systematic review of 19 clinical studies found that miR-155 was associated with cancer treatment outcomes in a context-dependent way, ...
A review finds that miR-125b, miR-375 and miR-451 are linked to breast cancer chemoresistance through distinct, context-dependent mechanisms that require ...
A new review argues that the slow clinical translation of RNA 5-methylcytosine cancer biomarkers stems from a lack of analytically ...
The choice of CEACAM5, historically known as carcinoembryonic antigen (CEA) and assigned the cluster designation CD66e, as the model analyte ...
A paired biopsy study finds that nasopharyngeal carcinoma tissue harbors distinct bacterial communities linked to Epstein-Barr virus activity and immune ...
A pan-cancer computational study identified the buckwheat-derived compound fagopyrine as a strong predicted binder to the AKT1 kinase, positioning it ...
New research shows that damaged extrachromosomal DNA is trapped in transcriptionally silent micronuclei, impairing cancer cell fitness and predicting better ...
A long-read RNA sequencing atlas of 144 paired tumor-normal samples across ten organs shows that gene expression changes converge across ...
A systematic review in Medical Oncology details how the HUSH complex silences retrotransposons through H3K9me3 deposition and how its dysregulation ...
New research in The FEBS Journal links mitochondrial DNA copy number in cancer cells to mutational load, tumor growth gene ...
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