• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Tuesday, August 26, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Reviews highlight new advances in our understanding of focal and sclerotic bone diseases

Bioengineer by Bioengineer
May 13, 2019
in Health
Reading Time: 4 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Providing expert insights on the pathogenesis and management of rare skeletal diseases such as fibrous dysplasia, Fibrogenesis Imperfecta Ossium, Melorheostosis, Osteopoikilosis, Camurati-Engelmann disease, osteomyelitis and Paget’s disease.

Recently, extraordinary progress has been made in our understanding of the mechanisms and molecular pathways underlying focal and sclerotic bone diseases, rare disorders which have a strong genetic component. This has already led to a clearer characterization of these conditions and, in several cases, has enabled the development of new therapeutic approaches.

The invited reviews featured in this special edition of ‘Calcified Tissue International‘ provide expert commentary and a valuable overview of advances in the knowledge of several rare focal and sclerotic bone diseases including Paget’s disease of bone and related syndromes, fibrous dysplasia of bone and McCune-Albright syndrome, Melorheostosis and Osteopoikilosis, chronic non-bacterial osteomyelitis, as well as Camurati-Engelmann disease.

Although investigations into the molecular and genetic basis of these conditions have not yet yielded results for all the conditions, the advances have overall led to a better understanding of the causes of the particular lesions. In certain cases, like Paget’s disease, this knowledge has vastly improved diagnosis and management of the disorder. In other cases, such as with Camurati-Engelmann disease, it has led to research into a potentially new therapeutic approach. Finally, in other disorders where a genetic basis is suspected but not yet pinpointed, advances have still been made in the management of these disorders, for example in the case of Fibrogenesis Imperfecta Ossium.

Professor Stuart Ralston, special issue editor, stated: “These state-of-the-art reviews by leading experts show the immense progress which has been made in our understanding of rare skeletal diseases. Indeed, for diseases such as Paget’s, tremendous leaps have been made which now mean a better management of the disease is possible. In other diseases, these advances mean new avenues for therapeutic intervention are now on the horizon. Although there is still a long way to go, the hope is that with increasing knowledge we will be able to continually improve patient management from diagnosis to treatment. We thank the authors for contributing these outstanding publications.”

###

Read, download and share:

* Focal and Sclerotic Bone Diseases (Editorial)



Ralston, S.H. & Rizzoli, R. Calcif Tissue Int (2019).

https://doi.org/10.1007/s00223-019-00556-7

https://rdcu.be/bBCog

* Paget’s disease of bone



Gennari, L., Rendina, D., Falchetti, A. et al. Calcif Tissue Int (2019). https://doi.org/10.1007/s00223-019-00522-3

https://rdcu.be/bymFv

* Rare Inherited forms of Paget’s Disease and Related Syndromes



Ralston, S.H. & Taylor, J.P. Calcif Tissue Int (2019).

https://doi.org/10.1007/s00223-019-00520-5

https://rdcu.be/bymF8

* Fibrous Dysplasia of Bone and McCune-Albright Syndrome: A Bench to Bedside Review



Hartley, I., Zhadina, M., Collins, M.T. et al. Calcif Tissue Int (2019). https://doi.org/10.1007/s00223-019-00550-z

https://rdcu.be/bzK6Z

* Melorheostosis and Osteopoikilosis: A Review of Clinical Features and Pathogenesis

Wordsworth, P. & Chan, M. Calcif Tissue Int (2019).

https://doi.org/10.1007/s00223-019-00543-y

* Chronic Non-bacterial Osteomyelitis: A Review



Buch, K., Thuesen, A.C.B., Brøns, C., Schwarz, P. Calcif Tissue Int (2018). https://doi.org/10.1007/s00223-018-0495-0

https://rdcu.be/byynN

* Camurati-Engelmann Disease



Van Hul, W., Boudin, E., Vanhoenacker, F.M. et al. Calcif Tissue Int (2019). https://doi.org/10.1007/s00223-019-00532-1

https://rdcu.be/bymD0

* Fibrogenesis Imperfecta Ossium



Bhadada, S.K., Dhaliwal, R., Dhiman, V. et al. Calcif Tissue Int (2019). https://doi.org/10.1007/s00223-019-00547-8

https://rdcu.be/bBCoJ

About Calcified Tissue International

Calcified Tissue International & Musculoskeletal Research is a peer-reviewed journal which publishes original preclinical, translational and clinical research, and reviews concerning the structure and function of bone, and other musculoskeletal tissues in living organisms, as well as clinical studies of musculoskeletal disease. It includes studies of cell biology, molecular biology, intracellular signalling, and physiology, as well as research into the hormones, cytokines and other mediators that influence the musculoskeletal system. The journal also publishes clinical studies of relevance to bone disease, mineral metabolism, muscle function, and musculoskeletal interactions. 2017 Impact Factor: 3.293 / 5 Year Impact Factor: 3.315
Editors in Chief: Stuart Ralston and René Rizzoli; Musculoskeletal Research Section Editor: Roger Fielding

Media Contact
L. Misteli
[email protected]
https://www.iofbonehealth.org/news/reviews-highlight-new-advances-our-understanding-focal-and-sclerotic-bone-diseases

Tags: DiagnosticsEndocrinologyGeneticsInternal MedicineMedicine/HealthMetabolism/Metabolic DiseasesMolecular BiologyOrthopedic MedicinePediatricsPhysiology
Share12Tweet8Share2ShareShareShare2

Related Posts

Targeted Prostate Screening: Reducing Harm through Age Stratification

August 26, 2025

Aortic Valve Guides Umbilical Artery Catheter Placement

August 26, 2025

Improved Stroke Outcomes for Older Patients in Collaborative Care

August 26, 2025

Identifying Late-Onset Sepsis Markers in Pediatric ICU

August 26, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    146 shares
    Share 58 Tweet 37
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    81 shares
    Share 32 Tweet 20

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

JUNO Successfully Completes Liquid Filling and Commences Data Acquisition

Targeted Prostate Screening: Reducing Harm through Age Stratification

Aortic Valve Guides Umbilical Artery Catheter Placement

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.