• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Monday, September 25, 2023
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

New report explains microbiome impact on glucose control

Bioengineer by Bioengineer
June 28, 2021
in Health
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Highlights how probiotic interventions can improve Type 2 diabetes management

IMAGE

Credit: Pendulum Therapeutics

San Francisco, CA, June 28, 2021 – A new study by Pendulum Therapeutics was presented at the American Diabetes Association’s (ADA) 81st (Virtual) Scientific Sessions, the preeminent global conference for diabetes clinicians, researchers, and professionals where cutting-edge science and advances in diabetes research, prevention, and care are discussed. The findings shine a light on proprietary probiotic formulations that may be used to help patients with Type 2 Diabetes (T2D).

The research report entitled, “Changes in Circulating Metabolites, Including Butyrate, Points to Underlying Mechanism of a Probiotic Intervention That Improves Postprandial Hyperglycemia in Type 2 Diabetes,” is believed to be the first of its kind. Its findings show Pendulum Glucose Control increases circulating butyrate and ursodeoxycholic acid (UDCA), a secondary bile acid in people with T2D, and supports the mechanism for improvement in glucose control.

According to the Centers for Disease Control and Prevention (CDC), more than 30 million Americans have T2D. New research shows that T2D is linked to an imbalance in the gut microbiome. Over time, people with T2D lose functionality of the beneficial bacteria strains that help digest dietary fiber and produce butyrate, a key molecule needed for managing insulin secretion and action, encouraging glucose regulation.

Previous studies have shown that there are three pillars to managing diabetes without the use of drugs: diet, exercise, and the microbiome. This new research helps explain why microbiome management is critical to keeping blood glucose under control.

“This study, part of an ongoing series, is adding to the body of knowledge on the microbiome and its role in metabolic disease including Type 2 Diabetes,” said Orville Kolterman, MD, Chief Medical Officer at Pendulum Therapeutics and Principal Investigator of the study. “This data builds upon the research Pendulum Therapeutics presented at ADA’s 79th Scientific Sessions two years ago. Our initial presentation showcased the efficacy of Pendulum’s proprietary microbiome synbiotic formulation (Pendulum Glucose Control) and its ability to improve glucose control in patients with Type 2 Diabetes. This newest data will further inform the development of a portfolio of products that target the microbiome as a pathway to augment the dietary management of impaired glucose metabolism and other metabolic diseases.”

Pendulum Glucose Control, Pendulum Therapeutics’ ground-breaking, flagship product, is featured in the American Diabetes Association’s selection of thought-leadership videos that will debut at ADA’s 81st Scientific Sessions.

“The microbiome is proving to be an exciting and provocative area of study. Multiple studies to date point to the microbiome’s integral role in disease management,” said Colleen Cutcliffe, Pendulum’s Co-Founder and Chief Executive Officer. “At Pendulum Therapeutics, we are committed to a methodical, rigorous, science-based approach to developing microbiome interventions. These data are affirming as we continue to pursue a portfolio of products to improve overall health.”

###

About Pendulum Therapeutics

Pendulum Therapeutics believes probiotics – developed using evidence-based microbiome science and DNA sequencing – can help heal the body from within. Armed with nine patents and five pending, the company introduced its flagship product Pendulum Glucose Control in 2020 and demonstrated its efficacy in lowering blood sugar spikes and reducing A1C in a published clinical trial. Founded in 2012 by a diverse team of scientists with deep microbiology, biochemistry, computational and clinical expertise, Pendulum has raised $105 million to date from Meritech Capital, Sequoia Capital, True Ventures, Khosla Ventures, AME Cloud Ventures, and Mayo Clinic among others. Pendulum Therapeutics is headquartered in San Francisco.

Media Contact
Stephen McCauley
[email protected]

Tags: BacteriologyClinical TrialsDiabetesHealth CareMedicine/HealthMetabolism/Metabolic DiseasesMicrobiologyNutrition/Nutrients
Share12Tweet8Share2ShareShareShare2

Related Posts

Study determined that women and men face some common, but also many different barriers, and barriers differ by global region

Global study provides new insights into barriers to effective cardiovascular rehabilitation for women and why women are less likely to participate

September 25, 2023
Eye Exam System

NIH awards researchers $1.2M to develop robotic eye examination system

September 22, 2023

Nanofluidic device generates power with saltwater

September 22, 2023

Clinical trial to test immune modulation strategy for hospitalized COVID-19 patients begins

September 22, 2023
Please login to join discussion

POPULAR NEWS

  • blank

    Microbe Computers

    58 shares
    Share 23 Tweet 15
  • A pioneering study from Politecnico di Milano sheds light on one of the still poorly understood aspects of cancer

    34 shares
    Share 14 Tweet 9
  • Fossil spines reveal deep sea’s past

    34 shares
    Share 14 Tweet 9
  • Scientists go ‘back to the future,’ create flies with ancient genes to study evolution

    75 shares
    Share 30 Tweet 19

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Researchers pioneer safe chemotherapy methods for treating bacterial infections

ETRI unveiled hyper-realistic technologies for the metaverse world

Global study provides new insights into barriers to effective cardiovascular rehabilitation for women and why women are less likely to participate

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 57 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In