Cancer

New research reveals that the ubiquitin-editing enzyme A20 promotes the degradation of the pro-tumor protein osteopontin in hepatocellular carcinoma, offering...

A Phase 1 trial found that combining the ATR inhibitor ceralasertib with the PARP inhibitor olaparib was generally well tolerated...

A new narrative review argues that individualized dietary interventions, grounded in tumor metabolism and the gut microbiome, should be integrated...

A long-term study of 344 oropharyngeal cancer survivors finds excellent overall quality of life after curative radiotherapy, with radiation dose...

A new Nature Reviews Clinical Oncology review charts how HER2-targeted therapies, led by trastuzumab deruxtecan, are driving a shift from...

A statewide coalition led by UT MD Anderson has launched the Texas Lone Star Cervical Cancer Elimination Plan 2027-2032, targeting...

A new review details how disrupted mitochondrial homeostasis and activated retrograde signaling drive cancer progression and may open fresh therapeutic...

A London quality improvement project found that starting tube feeding on the same day as head and neck flap surgery...

A tree shrew model shows that radiation-induced fibrosis of the tensor veli palatine muscle, driven by oxidative stress and TGF-beta...

Interviews with eighteen young adult cancer survivors reveal cautious optimism that generative AI chatbots could supplement survivorship care through personalized,...

Researchers have shown that the matrix protein fibronectin reprograms macrophages in damaged dental pulp into pro-angiogenic cells, enhancing blood vessel...

Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression...

A study of more than 1,100 high-risk individuals links abdominal fat measured by CT scans to lung cancer and shows...

A Ghanaian study of 38 children with non-Hodgkin lymphoma found that BCL-2 expression and tumor spread significantly predicted survival, with...

Researchers built a four-gene signature based on propionate metabolism that stratifies colorectal cancer patients by survival risk and links tumor...

A survey of 1,063 Lebanese medical students and residents found that despite moderate knowledge of skin cancer and widespread sunscreen...

A new study shows that 5-alpha-reductase inhibitor therapy can trigger macrophage pyroptosis, HMGB1–AGER-driven epithelial senescence and club-cell reprogramming in the...

A Swiss real-world study of 38 palliative care patients found that rapid intravenous opioid titration reduced median pain scores from...

Wistar Institute scientists report that combining the kidney cancer drug axitinib with a 4-1BB agonist overcame myeloid cell suppression and...

A new review in Molecular Cancer explains how tumor-derived exosomes act as mobile signaling hubs that spread immune suppression, drive...