Cancer

A new review in Medical Oncology examines how organoid and assembloid technologies could overcome the limits of conventional models in...

A study in Medical Oncology reports that the E3 ubiquitin ligase RNF152 is low in clear cell renal cell carcinoma,...

A machine-learning model based on six serum proteins diagnosed esophageal squamous cell carcinoma with AUCs of 0.932 and 0.968 in...

Phase 3 DeLLphi-305 results show that adding tarlatamab to durvalumab as first-line maintenance therapy extended median overall survival by more...

Duke pathology researchers report that the membrane protein SERINC2 remodels phosphatidylserine to activate AXL signaling and reshape the brain immune...

A study of 3504 individual breast microcalcifications scanned with high-resolution 3D micro-CT shows that the tissue surrounding each calcium deposit...

A machine-learning 15-gene lactylation signature predicts prognosis and drug response in clear cell renal cell carcinoma, with CCNA2 identified as...

A Phase 1 trial presented at ESMO 2026 reports a 40% objective response rate at 130 mg for ISM6331, a...

A 15-year retrospective study of 13 patients at Beijing Tongren Hospital found that orbital mantle cell lymphoma typically presents as...

Researchers at HZI and HIPS activated silent bacterial genes to discover myxoglucamides, unusual natural products that bind the cancer-associated enzyme...

A case report in Oncotarget describes how an international molecular tumor board weighed treatment options for a 52-year-old woman with...

A cohort study of 105 breast radial sclerosing lesions with atypia found that three-year malignancy risk ranged from 29.2 percent...

An integrative analysis combining sequencing, Mendelian randomization, tissue cohorts and a luciferase assay identifies miR-183-3p as a candidate ESR1 3′-UTR-binding...

Obesity appears to disable one of the body's own defenses against breast cancer, according to a new study from Huntsman...

Triple-negative breast cancer represents a particularly aggressive subtype of the disease, characterized by the absence of hormone receptors and HER2...

Phase 3 trial results presented at ESMO 2026 show that adding personalized mRNA vaccine intismeran to pembrolizumab reduces melanoma recurrence...

A Virologica Sinica study found that gastric cancer patients show a marked expansion of Anelloviridae in blood alongside novel virus...

Genome sequencing of normal oesophageal tissue shows that chemotherapy and chemoradiotherapy select for distinct mutant clones in healthy cells, including...

The Phase 3 DESTINY-Lung04 trial reports that first-line single-agent trastuzumab deruxtecan significantly improved progression-free survival and response rates versus pembrolizumab...

UCLA researchers identified a GGPP-Rho-YAP signaling pathway in hepatic stellate cells around MASLD-related liver tumors that statins suppressed in laboratory...