• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Sunday, August 10, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Chemistry

Biomedical sciences researcher gets $2.3 million grant to study inflammation in infectious diseases

Bioengineer by Bioengineer
April 21, 2021
in Chemistry
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Georgia State University

ATLANTA–Dr. Jian-Dong Li, professor and director of the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.3 million federal grant to study how overactive inflammatory response is caused in infectious diseases and to further develop novel anti-inflammatory therapeutics.

The grant from the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders will be used to understand excess mucus production and inflammation in otitis media, an infection of the middle ear, the air-filled space behind the eardrum.

Otitis media, the most common childhood bacterial infection and the leading cause of conductive hearing loss in children, remains a major health problem and substantial socioeconomic burden. Current vaccines targeting Streptococcus pneumoniae, a key bacterial pathogen causing this infectious disease, have a limited impact. The inappropriate use of antibiotics also has led to increased antibiotic resistance.

“There is an urgent need for developing innovative non-antibiotic therapeutic agents for suppressing excess mucus overproduction and inflammation in otitis media,” said Li, also a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity.

Mucin, a major protein component in mucus, plays a central role in mucosal defense by providing a physical barrier and trapping pathogens. However, if uncontrolled, excessive mucin production can cause conductive hearing loss in middle ear infection and mucus obstruction in lung infections.

Mucin needs to be tightly regulated, but the molecular mechanisms for tight regulation of mucin production remain largely unknown. Understanding the key regulators that increase mucin production may help to identify novel therapeutic targets and lead to the development of new therapeutic agents for suppressing mucus.

“Our goal is to elucidate the molecular mechanisms underlying otitis media pathogenesis and identify novel therapeutic targets towards developing a novel ototopical eardrop for treating inflammation and mucus overproduction and improving hearing,” Li said.

For more information about the grant, visit https://reporter.nih.gov/search/e43SHnRTL0qhCnUx7Seo4A/project-details/10229198.

###

Media Contact
LaTina Emerson
[email protected]

Original Source

https://news.gsu.edu/2021/04/20/biomedical-sciences-researcher-gets-2-3-million-federal-grant-to-study-inflammation-in-infectious-diseases/

Tags: Hearing/SpeechInfectious/Emerging DiseasesMedicine/HealthPediatricsPharmaceutical Science
Share12Tweet8Share2ShareShareShare2

Related Posts

Uranium Complex Converts Dinitrogen to Ammonia Catalytically

Uranium Complex Converts Dinitrogen to Ammonia Catalytically

August 10, 2025
Al–Salen Catalyst Powers Enantioselective Photocyclization

Al–Salen Catalyst Powers Enantioselective Photocyclization

August 9, 2025

Bacterial Enzyme Powers ATP-Driven Protein C-Terminus Modification

August 9, 2025

Machine-Learned Model Maps Protein Landscapes Efficiently

August 9, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Molecules in Focus: Capturing the Timeless Dance of Particles

    138 shares
    Share 55 Tweet 35
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    77 shares
    Share 31 Tweet 19
  • Modified DASH Diet Reduces Blood Sugar Levels in Adults with Type 2 Diabetes, Clinical Trial Finds

    56 shares
    Share 22 Tweet 14
  • Overlooked Dangers: Debunking Common Myths About Skin Cancer Risk in the U.S.

    61 shares
    Share 24 Tweet 15

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Uranium Complex Converts Dinitrogen to Ammonia Catalytically

Kombucha’s Pharmaceutical Potential: Production, Patents, Challenges

Enhancing Lithium Storage in Zn3Mo2O9 with Carbon Coating

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.