{"id":46941,"date":"2017-10-10T20:23:50","date_gmt":"2017-10-10T19:23:50","guid":{"rendered":"https:\/\/bioengineer.org\/unexpected-regulation-of-transcription-factors-critical-to-development\/"},"modified":"2017-10-10T20:23:50","modified_gmt":"2017-10-10T19:23:50","slug":"unexpected-regulation-of-transcription-factors-critical-to-development","status":"publish","type":"post","link":"https:\/\/bioengineer.org\/unexpected-regulation-of-transcription-factors-critical-to-development\/","title":{"rendered":"Unexpected regulation of transcription factors critical to development"},"content":{"rendered":"

(University of Massachusetts at Amherst) A team of developmental biologists at the University of Massachusetts Amherst led by Dominique Alfandari, with others at MIT, report in a new paper that they have for the first time described how two transcription factors that are 'absolutely essential for human development' are regulated by a cell surface metalloprotease known as ADAM13. The discovery adds to knowledge of how cells migrate in vertebrate embryos, how stem cells differentiate and how cancer cells metastasize.<\/p>\n","protected":false},"excerpt":{"rendered":"

(University of Massachusetts at Amherst) A team of developmental biologists at the University of Massachusetts Amherst led by Dominique Alfandari, with others at MIT, report in a new paper that they h..<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[185],"tags":[],"class_list":["post-46941","post","type-post","status-publish","format-standard","hentry","category-science-news"],"_links":{"self":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts\/46941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/comments?post=46941"}],"version-history":[{"count":0,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts\/46941\/revisions"}],"wp:attachment":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/media?parent=46941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/categories?post=46941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/tags?post=46941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} BIOENGINEER.ORG

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