A new, updated account of poroid fungi in North America
Poroid fungi, commonly known as "polypores," are among the most frequently encountered fungi throughout the year because of their large ...
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<\/p>\nStress takes various shapes in our daily lives, from relentless work demands to the constant rush of the school run. But ignoring high stress levels can lead to serious health issues like depression and Alzheimer’s disease.<\/p>\n
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Credit: Andreas Schikora, CC BY-SA 4.0, via Wikimedia Commons<\/p>\n
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Stress takes various shapes in our daily lives, from relentless work demands to the constant rush of the school run. But ignoring high stress levels can lead to serious health issues like depression and Alzheimer’s disease.<\/p>\n
So what if checking your stress levels at home became the norm? Thanks to nanoparticles, this possibility is drawing closer.<\/p>\n
In a\u00a0new study published in the journal Talanta<\/em>, a team from China and the UK have produced a new and improved detector that can accurately measure levels of cortisol \u2013 a stress biomarker in the blood.<\/p>\n Tong Ji, a current part-time PhD student and a senior technician at\u00a0Xi’an Jiaotong-Liverpool University (XJTLU), China, is the first author of the study. She says, “A cost-effective, easily reproducible, and easy-to-use point-of-care testing device that accurately measures cortisol levels has long been sought. It could make a huge difference to an appropriate and speedy diagnosis of high cortisol levels, drastically improving people’s lives.”<\/p>\n The devices currently available generally contain electrodes that have poor stability in different and fluctuating conditions, such as changing pH and temperature. This gives the devices a short shelf life and makes them difficult to produce commercially.<\/p>\n “Current cortisol detectors have reference electrodes with a silver layer that is easily oxidised and unstable in electrochemical measurements,” says Ji. “In this study, we used iridium oxide nanoparticles to cover the silver layer. This modification improves the stability, sensitivity and reproducibility of cortisol detection in point-of-care devices.”<\/p>\n Dr Qiuchen Dong, an assistant professor at XJTLU and corresponding author, adds, “This is the first time iridium oxide has been used in this way. Our team have produced a simple, low-cost cortisol measuring device that detects cortisol molecules at a concentration 3,000 times lower than the normal range of cortisol in our blood. This makes our device sensitive enough for commercial use.”<\/p>\n The iridium oxide-modified electrodes have also improved the selectivity of testing.\u00a0Dr Graham Dawson, XJTLU Associate Professor and co-author, says, “One problem with the current solutions is that there is much similarity between cortisol and other hormones such as progesterone, testosterone, and corticosterone. This means it is difficult for the detectors to tell them apart. Our iridium oxide-modified electrode is selective enough to distinguish the different hormones and helps to solve this issue.”<\/p>\n Talanta<\/p>\n<\/p><\/div>\n 10.1016\/j.talanta.2024.126776 <\/i><\/p>\n<\/p><\/div>\n Experimental study<\/p>\n<\/p><\/div>\n Not applicable<\/p>\n<\/p><\/div>\n Iridium oxide-modified reference screen-printed electrodes for point-of-care portable electrochemical cortisol detection<\/p>\n<\/p><\/div>\n 30-Aug-2024<\/p>\n<\/p><\/div>\n The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article.<\/p>\n<\/p><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":" Stress takes various shapes in our daily lives, from relentless work demands to the constant rush of the school run. But ignoring high stress levels can lead to serious health issues like depression and Alzheimer’s disease. Credit: Andreas Schikora, CC BY-SA 4.0, via Wikimedia Commons Stress takes various shapes in our daily lives, from relentless […]<\/p>\n","protected":false},"author":1,"featured_media":232446,"comment_status":"","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_override_bookmark_settings":[],"jnews_social_meta":[],"jnews_review":[],"enable_review":"","type":"","name":"","summary":"","brand":"","sku":"","good":[],"bad":[],"score_override":"","override_value":"","rating":[],"price":[],"jnews_override_counter":[],"footnotes":""},"categories":[267],"tags":[],"class_list":["post-232445","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biology"],"_links":{"self":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts\/232445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/comments?post=232445"}],"version-history":[{"count":0,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/posts\/232445\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/media\/232446"}],"wp:attachment":[{"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/media?parent=232445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/categories?post=232445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bioengineer.org\/wp-json\/wp\/v2\/tags?post=232445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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A new, updated account of poroid fungi in North America
Few anti-immigration users dominate most of UK-based anti-immigration content on Twitter with rapid spread and high polarization
Agriculture accelerated human genome evolution to capture energy from starchy foods
As dogs age, their owner-assessed quality of life predictably declines, with higher mortality seen at quality of life below 76% of the maximum score – though many dogs have high quality of life even when at predicted lifespan
Samples from bottled water, tap water and household-treated tap water in San Francisco Bay Area indicate that all sources may have potential health risks, largely from trihalomethanes
Young male northern elephant seals are captured on camera returning to a deep sea cabled observatory off Canada’s British Columbia coast, demonstrating new insight into fish foraging behavior
Both cats and dogs often enjoy playing fetch with their owners
Collaborative research to benefit coastal flounder populations and fishers
New book ‘Macroevolutionaries’ explores intersection of evolution, art and popular culture
SpinMagIC: ‘EPR on a chip’ ensures quality of olive oil and beer
City of Hope to offer second opinions for cancer patients in Southeast Asia via a collaboration agreement with the Healthway Cancer Care Hospital
A new role for intelligent tutors powered by AI in brain surgery?
At-risk butterflies more likely to survive with human help
PFAS influence the development and function of the brain
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