• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Friday, September 5, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Wall awarded $385,000 grant to study amyloidosis treatment options

Bioengineer by Bioengineer
October 6, 2020
in Health
Reading Time: 2 mins read
0
IMAGE
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: UTHSC

Memphis, Tenn. (October 6, 2020) – Jonathan Wall, PhD, professor in the University of Tennessee Health Science Center’s Graduate School of Medicine in Knoxville and director of the Amyloidosis and Cancer Theranostics, has been awarded a two-year grant totaling $385,000 from the National Institute on Aging, part of the National Institutes of Health to study new treatments for systemic amyloidosis.

“Our studies will focus on the development and characterization of engineered immune cells (macrophages) that are capable of enhanced destruction of amyloid due to the expression of a synthetic amyloid-reactive receptor,” Dr. Wall said. “This receptor will be constructed in the laboratory and introduced into the cells, which will then be tested for their ability to destroy amyloid deposits. Current therapies are directed toward decreasing the amount of precursor protein that is available for amyloid formation, thereby slowing the disease progression. However, our team has several programs that focus on developing ways to remove the toxic amyloid deposits from the affected organs.”

The project is titled, “Development of chimeric antigen receptor-expressing macrophages for enhanced phagocytosis of systemic amyloid.” Typically, systemic amyloidosis develops when amyloid fibrils, or combined antibody-related light chain proteins that deposit in organs, such as the heart, kidney, and peripheral nerves. This can occur in more than 30 different disorders and may cause severe organ failure. Because amyloid is resistant to natural clearance, treatment for the diseases generally involves blocking production of the proteins that cause amyloid. However, clearance of tissue amyloid has now become a major goal of many of the novel therapeutics being developed for these patients.

In other amyloid-related research, Dr. Wall also serves as the interim chief scientific officer for Attralus, Inc., a startup company launched through a license with the UT Research Foundation, which recently received $25 million to work on transformative medicines for systemic amyloidosis patients.

###

As Tennessee’s only public, statewide, academic health system, the mission of the University of Tennessee Health Science Center is to bring the benefits of the health sciences to the achievement and maintenance of human health through education, research, clinical care, and public service, with a focus on the citizens of Tennessee and the region. The main campus in Memphis includes six colleges: Dentistry, Graduate Health Sciences, Health Professions, Medicine, Nursing and Pharmacy. UTHSC also educates and trains medicine, pharmacy, and/or health professions students, as well as medical residents and fellows, at major sites in Knoxville, Chattanooga and Nashville. For more information, visit http://www.uthsc.edu. Find us on Facebook: facebook.com/uthsc, on Twitter: twitter.com/uthsc and on Instagram: instagram.com/uthsc.

Media Contact
Amber Carter
[email protected]

Tags: Medicine/Health
Share12Tweet8Share2ShareShareShare2

Related Posts

Addressing Emerging Pollutants in China: An In-Depth Review of Current Challenges, Knowledge Gaps, and Strategic Solutions

September 5, 2025

Enduring Benefits of OR Shadowing for New Nurses

September 5, 2025

Revolutionizing CAR Therapy for Thyroid Eye Disease

September 5, 2025

Mesenchymal Stem Cells’ Immunomodulation in Lung Diseases

September 5, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    149 shares
    Share 60 Tweet 37
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Modified DASH Diet Reduces Blood Sugar Levels in Adults with Type 2 Diabetes, Clinical Trial Finds

    61 shares
    Share 24 Tweet 15

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Ultra-Compact Plasmonic Nanocavity Boosts Magnetic SHG

Impact of Vegetable Waste on Labeo Rohita Growth

Addressing Emerging Pollutants in China: An In-Depth Review of Current Challenges, Knowledge Gaps, and Strategic Solutions

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.