• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Tuesday, October 7, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Targeting epilepsy with electrodes on the head

Bioengineer by Bioengineer
February 12, 2019
in Health
Reading Time: 3 mins read
0
IMAGE
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Researchers to develop patient-specific method for noninvasive brain stimulation

IMAGE

Credit: Photo: Bart van Overbeeke.

Stimulating the brain with implanted electrodes is a successful, but very drastic measure. Researchers from Eindhoven University of Technology, Kempenhaeghe, Philips and Gent University will therefore be working on a method to stimulate the brain using electrodes that are placed on the head rather than inside it. Their goal is to customize treatment for patients with severe epilepsy. Incidentally, they will also settle the scientific discussion about the efficacy of non-invasive electrical neurostimulation.

Epilepsy affects approximately 120,000 people in the Netherlands, about thirty percent of whom do not respond to medication and remain prone to seizures. For this group, electrical brain stimulation can be a solution. DBS (deep brain stimulation), with electrodes deep in the brain, has already proven to be effective. The electrodes must be positioned accurately so that they stimulate exactly the right brain area. This accuracy issue is still a bottleneck for non-invasive neurostimulation, because it is not yet sufficiently known where exactly the stimulation needs to be targeted and it is even more difficult to reach the right place in the brain from the outside.

Personalized

The researchers expect a new Philips medical instrument to provide the solution for focal seizures; seizures in a specific part of the brain. This is a system with 256 electrodes that not only measures brain activity (EEG), but can also apply very targeted current. Project leader and technical research leader Rob Mestrom of Eindhoven University of Technology: “This instrument therefore offers us the unique opportunity to see more accurately than before where exactly in the brain an epileptic seizure takes place. We can then stimulate precisely that point and measure the effect directly. This gives a personalized approach, because it is tailored to the readings of the individual patient.”

The basic idea of the project, called PerStim, is simple, says Paul Boon, clinical research leader and professor at UGent and TU Eindhoven. “When we have located the source of the seizure, we target an electrical stimulus at that spot that is exactly the opposite of the measured activity. As a result, the seizure should be ‘extinguished’. We will investigate this with both direct and alternating currents.”

Clinical testing

The first step in the research project is the development of a personalized calculation model to accurately reconstruct the epileptic focus. The researchers will then determine the stimulation parameters to achieve the desired focus of the stimulation. Then they will look at how they can best measure the effect of stimulation. The results will gradually be applied in clinical trials. Two PhD students and a postdoc will be appointed for the project. The research, with a budget of 1.9 million euros, is part of EindhovenMedTech Innovation Center (e/MTIC), a broad research collaboration between TU/e, Kempenhaeghe and Philips, among others.

Question marks

Last year, the efficacy of non-invasive brain stimulation was questioned in the leading scientific journal Cell. In a study published in Nature Communications using measurements in the brains of recently deceased subjects, most of the electrical stimuli did not reach the intended area at all. Paul Boon: “Our research will enable us to answer the question of whether it works, and we will show you how you can apply this in a personalized way to focal epilepsy.”

###

Media Contact
Rob Mestrom
[email protected]

Tags: BiotechnologyClinical TrialsHealth Care Systems/ServicesMedicine/HealthneurobiologyNeurochemistryParkinson
Share12Tweet7Share2ShareShareShare1

Related Posts

SMOC1 Identified as Key Gene in β-Cell Dedifferentiation

SMOC1 Identified as Key Gene in β-Cell Dedifferentiation

October 7, 2025

NICU Workers’ Challenges in Hidalgo County Border Community

October 7, 2025

Fra-1 Drives Gastric Cancer via Macrophage and HMGA2

October 7, 2025

Pelvic Dashboard Injuries After Hip Replacement Explored

October 7, 2025
Please login to join discussion

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    119 shares
    Share 48 Tweet 30
  • New Study Reveals the Science Behind Exercise and Weight Loss

    96 shares
    Share 38 Tweet 24
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    94 shares
    Share 38 Tweet 24
  • Ohio State Study Reveals Protein Quality Control Breakdown as Key Factor in Cancer Immunotherapy Failure

    74 shares
    Share 30 Tweet 19

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Next-Gen Multi-Color Lasers Miniaturized on a Single Chip

SMOC1 Identified as Key Gene in β-Cell Dedifferentiation

Scientists Develop ChatGPT-Inspired AI Model to Craft One of the Most Comprehensive Mouse Brain Maps Yet

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 63 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.