Pig Liver Perfusion Coagulation Breakdown Examined for Human Clinical Support
A narrative review identifies porcine von Willebrand factor and sinusoidal clearance as central mechanisms behind rapid platelet loss during normothermic ...
Tag: Xenotransplantation
ELPAT Congress Examines Ethics, Technology, and Vulnerability in Organ Transplantation
A special issue of Transplant International presents research and position papers from the 6th ELPAT Congress on ethical, psychosocial, and ...
Neural organoids go functional: measuring living brain circuits in a dish
A new review details how calcium imaging, patch clamp and multielectrode arrays now measure activity in human neural organoids at ...
Blood-clotting protein’s cousin keeps stem cells resting and transplants thriving
A one-hour exposure to activated protein C keeps human blood stem cells quiescent and improves their short-term serial engraftment in ...
Muscle repair gene CSRP3 works in pigs but not mice, study finds
A new study shows the CSRP3 gene is essential for satellite cell differentiation and muscle regeneration in pigs but dispensable ...
Pioneering Cardiac Xenotransplantation: Bridging Mortality in Pediatric Heart Disease
This review examines the clinical outcomes, pediatric preclinical evidence, and ethical considerations relevant to candidate selection for pediatric cardiac xenotransplantation, ...
2026 Medical Innovation Forum Reports Organ Freezing, Preclinical Cancer Therapy and AI
The 2026 World Medical Innovation Forum showcased experimental precision-frozen pig organs, a preclinical pancreatic-cancer immunotherapy, AI-enabled cardiovascular screening and a ...
Pig Organs at Scale: The Hidden Logistics Behind Xenotransplantation
A new review argues that the future of pig-to-human organ transplants depends less on immunology than on building an industrial-scale ...
Robotic Surgery, Machine Perfusion and AI Converge at Landmark Liver Transplant Congress
The 30th ILTS Congress in Singapore showcased robotic donor surgery, machine perfusion biomarkers, AI-driven prediction and xenotransplantation milestones, revealing a ...
How European Scientists Quietly Shaped the Rise of Pig-to-Human Organ Transplants
A new editorial in Transplant International highlights the pivotal and often overlooked contributions of European scientists to the genetic engineering, ...
Hidden Sugar Signals on Pig Organs May Decide Xenotransplant Success
A new review argues that sugar-based signaling through Siglec receptors and complement Factor H forms a hidden regulatory layer determining ...
From Dish to Living Brain: How Lab-Grown Human Microglia Are Rewriting Neuroimmune Research
A new review charts how stem cell-derived human microglia, brain organoids and chimeric mice are overcoming the genetic and environmental ...
Groundbreaking Study Advances Pig-to-Human Kidney Transplantation
In a groundbreaking advancement destined to reshape the future of organ transplantation, an international team of researchers has unveiled unprecedented ...
Porcine Heart Transplant
The successful transplantation of a genetically modified porcine heart into a living human marks a significant milestone in the field ...
Charting the Future of Genetically Modified Pig Heart Transplants: Insights from the Second Patient
In a remarkable advancement for xenotransplantation, a surgical breakthrough at the University of Maryland Medical Center has showcased the potential ...
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