Tag: sickle cell disease

A systematic review in Annals of Hematology finds that pyruvate kinase activators improve hemoglobin and reduce transfusion needs in PKD ...

A retrospective cohort study found pediatric patients with sickle cell disease-associated osteonecrosis of the femoral head experienced significantly higher total ...

A pilot study evaluating virtual reality headsets among hospitalized adults with sickle cell disease demonstrated high acceptability, low side effects, ...

The first University of Dodoma scientific conference on health compiled research showing major gains in maternal survival and kidney transplantation ...

A cross-sectional investigation conducted at the University of Benin Teaching Hospital in Benin City, Edo State, Nigeria, has found that ...

A systematic review of 21 studies finds CRISPR/Cas9 therapies for beta-thalassemia and sickle cell disease achieve high transfusion independence and ...

A two-year registry analysis from Dawadmi, Saudi Arabia, found very low prevalence of hemoglobinopathies and viral hepatitis among people undergoing ...

A modelling study of England's 2019/2020 screening cohort estimates that replacing paternal blood testing with NIPT in the sickle cell ...

A decision tree model estimates that a rigorous accuracy study of NIPT for sickle cell screening in England would require ...

A systematic review of 18 qualitative studies across nine African countries identifies government funding, stigma, community knowledge-sharing and screening options ...

A national spatial analysis of 280 Ugandan health-facility catchments identified the highest-priority zones for strengthening essential sickle cell disease services, ...

A German claims data analysis found that documented sickle cell disease prevalence rose from 2.75 to 10.50 per 100,000 between ...

A retrospective Kenyan study of 773 people found MCV had near-chance accuracy for detecting haemoglobinopathies, with sickle cell disease phenotypes ...

A single-center observational study found that older age, male sex and smoking were associated with cerebral aneurysms in sickle cell ...

A systematic review of 58 studies finds that transfusion-based stroke prevention established by the STOP trials remains the cornerstone for ...

A case-control study in Saudi Arabia finds that caregivers of children with Sickle Cell Disease report significantly higher rates of ...

A 2026 review summarizes advances in CRISPR-Cas9 precision, delivery and primary-cell engineering for genetic diseases and diabetes, while the available ...

A Guadeloupe study found increased platelet activation and caspase-1 activity in adults with sickle cell disease at steady state, with ...

UCLA physician-scientist Donald Kohn’s election to the National Academy of Medicine honors decades of work advancing blood stem cell gene ...

A sweeping narrative review charts how molecular genetics turned non-malignant blood disorders into the proving ground for modern diagnostics and ...