Osimertinib and Selinexor Team Up Against Aggressive T-Cell Leukemia in Preclinical Study
A preclinical study reports that the EGFR inhibitor osimertinib and the XPO1 inhibitor selinexor synergistically deplete c-MYC and trigger nucleolar ...
Tag: selinexor
Selinexor shows cytotoxic activity against BRAF-mutant pediatric glioma in 3D cultures
An FDA-approved nuclear export inhibitor killed lab-grown pediatric glioma cells carrying BRAFV600E and, combined with a MEK inhibitor, suppressed regrowth ...
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