![Preclinical Evaluation Assesses [11C]Onalespib for Cancer and Brain PET Imaging](https://bioengineer.org/wp-content/uploads/2026/11/stackrss-featured-2645-350x250.jpg)
Preclinical Evaluation Assesses [11C]Onalespib for Cancer and Brain PET Imaging
A preclinical evaluation of the radiolabelled Hsp90 inhibitor onalespib demonstrated tumour binding but revealed rapid metabolism and negligible brain penetration.
Tag: radiotracer
New Radiotracer Targets Brain Immune Cells With Unmatched Selectivity
Researchers validated 5-MOP, a tritium-labeled radioligand that binds CSF1R with 9.8 nM affinity and far greater kinase selectivity than the ...
New fluorinated glucose-based PET tracer shows promise for liver tumor imaging in mice
A newly synthesized PET tracer, 4-N-FDG-PBA, showed low liver background and GLUT-independent tumor uptake in preclinical mouse and cell studies.
Early PET/CT Scan Predicts Which HER2-Positive Breast Cancers Will Vanish Before Surgery
A prospective study finds that 68Ga-HER2 PET/CT scans after just two cycles of neoadjuvant therapy can predict which HER2-positive breast ...
AI-Designed PET Probe Reaches First Human Test for Imaging PARP-1 in Cancer
An AI-assisted design pipeline produced the gallium-68 PET tracer Ga-DOTA-FZPF, which targets PARP-1 and has now completed a first-in-human evaluation ...
New PET tracer homes in on bacterial infections by hijacking a sugar transport system unique to microbes
Researchers have engineered a glycosylated derivative of the common PET tracer FDG that is imported exclusively by the bacterial phosphotransferase ...
New Aβ-Tracking PET Radiotracer Revolutionizes Imaging in Monkeys
In groundbreaking developments within the field of neuroimaging, a recent study introduces a novel radiotracer that has shown promise in ...
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