Machine Learning Points to Chemoradiotherapy Benefit for Older Head and Neck Cancer Patients
A machine learning analysis of 1,525 SEER records finds that concurrent chemoradiotherapy is associated with roughly 30 percent better disease-specific ...
Tag: Radiotherapy
Chemoradiotherapy and Gene Methylation Emerge as Key Prognostic Signals in Localized Urothelial Cancer
A retrospective study of 170 patients finds that synchronous chemoradiotherapy significantly extends survival in muscle-invasive urothelial carcinoma, while methylation of ...
Daily CT Scans Reveal Hidden Tumour Texture Shifts During Head and Neck Radiotherapy
Researchers have developed a registration-consistent framework that turns routine daily cone-beam CT scans into a longitudinal measure of tumour texture ...
Probiotic Lozenges Cut Severe Mouth Sores in Head and Neck Radiotherapy Patients
A double-blind randomized trial found that probiotic lozenges containing Limosilactobacillus reuteri significantly reduced severe oral mucositis in head and neck ...
AI Fuses Scans and Radiation Doses to Predict a Deadly Head and Neck Cancer Complication
Researchers in China have built a deep-learning model that fuses CT, MRI, and 3D radiation dose data to predict which ...
How Tumors Survive Radiation: Plastic Cells and Tolerant Niches Drive Recurrence
A new review in Molecular Cancer reframes radioresistance as an ecosystem-level phenomenon in which plastic residual tumor cells survive radiation ...
PET Scans After Treatment Reveal Which Cervical Cancer Patients Face Highest Risk
A Swedish study of 133 patients shows that FDG-PET/CT response assessment after chemoradiotherapy strongly predicts recurrence and overall survival in ...
Drug Repurposing Finds IGF1R Inhibitor That Reverses Radioresistance in Head and Neck Cancer
Researchers in Taiwan mapped a 25-microRNA regulatory network driving radioresistance in head and neck cancer and used transcriptome-guided drug repurposing ...
Radiation Dose to Salivary Gland Predicts Lifelong Dry Mouth in Throat Cancer Survivors
A long-term study of 344 oropharyngeal cancer survivors finds excellent overall quality of life after curative radiotherapy, with radiation dose ...
Blood Test Tracks Tumour Oxygen Starvation and Predicts Radiotherapy Benefit in Bladder Cancer
A nanoparticle-enabled blood proteomics test can measure tumour hypoxia in bladder cancer patients, track it during radiotherapy and predict who ...
Molecular Fingerprints Reshape the Fight Against Childhood Brain Tumors Above the Tentorium
A comprehensive new review explains how ZFTA and YAP1 gene fusions have redefined the diagnosis and treatment of pediatric supratentorial ...
Male mice fare worse after heart radiation, revealing sex differences in cardiac injury
A Mayo Clinic study of irradiated mice shows that males develop inflammatory dilated cardiomyopathy and fibrosis after cardiac radiation while ...
Radiotherapy Still Matters in dMMR Endometrial Cancer, Researchers Warn in the Immunotherapy Era
A new Viewpoint in eClinicalMedicine argues that immune checkpoint inhibitors have not yet proven they can replace pelvic radiotherapy in ...
Mini-GRID Radiotherapy Curbs Cellular Senescence While Keeping Its Anti-Tumor Punch in Glioma Cells
A preclinical study finds that spatially fractionated mini-GRID radiotherapy preserves the growth-inhibitory effect of radiation in glioma cells while markedly ...
Weakness, Dizziness and Skin Burns: Ghanaian Women Reveal the Hidden Toll of Breast Cancer Radiotherapy
A qualitative study of seventeen Ghanaian women reveals that poorly managed physical side effects of breast cancer radiotherapy deter treatment ...
mRNA Vaccine Paired With Radiotherapy Shrinks HER2-Positive Lung Tumors in Mice
A HER2-targeted mRNA lipid nanoparticle vaccine combined with fractionated radiotherapy suppressed tumor growth and reprogrammed the immune microenvironment in a ...
Nanovaccine Built From Metal–Organic Frameworks Drives Tumours Into Full Retreat
A metal–organic framework nanovaccine co-delivering tumour antigens and STING agonists induced systemic tumour regression, immune memory and synergy with radiotherapy ...
The Hidden Architects of Colorectal Cancer: How Fibroblasts Drive Treatment Failure
A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to ...
Experts Endorse Barrier Films to Shield Skin From Radiation Burns in Cancer Therapy
An international MASCC expert panel has issued a clinical practice statement recommending barrier-forming topical agents, particularly the silicone-based gel StrataXRT, ...
Radiotherapy Fails to Improve Survival in Limb Liposarcoma, Study Finds
A propensity score-matched study of 153 patients suggests adjuvant radiotherapy does not improve overall or recurrence-free survival in limb liposarcoma, ...
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