Intrinsically disordered amino-terminal segments recruit molecular chaperones to protect emerging nascent proteins from cotranslational proteasomal degradation across yeast and human ...
Researchers found that the conserved gene Djvcp coordinates neoblast proliferation and apoptosis to maintain tissue homeostasis and enable blastema formation ...
A systematic review links the SEL1L-HRD1 quality control complex to neurodegeneration, cancer, metabolism and immunity.
In motor neuron–like cells, inhibiting the proteasome or autophagy reshapes extracellular vesicle cargo and spreads proteotoxic stress to recipient cells.
In a groundbreaking new study published in Nature Communications in 2026, researchers have uncovered a promising therapeutic target that could ...
