Tag: PI3K/Akt signaling

S-allylcysteine reduced uterine leiomyoma cell viability in primary culture while altering expression of PI3K/AKT-related genes, without establishing clinical efficacy.

New research reveals that the kinase NEK2 promotes trastuzumab resistance in gastric cancer by boosting WTAP/YTHDF1-dependent m6A modification of FN1 ...

A natural plant compound found in everyday foods such as buckwheat, apples and onions may offer protection against one of ...

A glycoprotein isolated from lion's mane mushroom reduced blood glucose, improved insulin sensitivity, and reshaped gut microbiota in diabetic mice.

A cross-species study shows that the gut bacterium Clostridium butyricum and its metabolite butyrate alleviate obesity by disrupting an LPS-EGR1 ...

A new review in Cancer Reports proposes that the extracellular matrix protein COL6A1, overexpressed in the fibrotic stroma of cholangiocarcinoma, ...

New research shows that the bile acid receptor FXR coordinates monocyte recruitment and Kupffer cell proliferation through CCR2 and CSF1/PI3K/Akt ...

A new study reveals that an AURKA-driven phosphorylation and SUMOylation cascade stabilizes the protein SPICE1, fueling prostate cancer's spread to ...

Recent research has unveiled the pivotal role of glutamine in the progression of colorectal cancer, spotlighting its influence through the ...

Colorectal cancer remains one of the most prevalent malignancies globally, posing significant challenges in terms of early detection, effective treatment, ...