Tag: PI3K/AKT pathway

A traditional 29-ingredient Mongolian medicine called Eerdun Wurile reduced brain damage and improved motor and cognitive function in mice following ...

A study in Frontiers in Microbiology found that TiaoJing ZhongYu Decoction improved metabolic and reproductive markers in a rat model ...

Extracellular vesicles from Clonorchis sinensis deliver microRNA Csi-miR-71a to hepatic stellate cells, suppressing liver fibrosis by targeting Scube3 and inhibiting ...

A study in rodent and cellular models demonstrates that the traditional Tibetan medicine Renqing Mangjue delays gastric precancer progression by ...

Oncologists documented circulating tumor DNA clearance and complete metabolic response in a patient with a rare marker-negative mediastinal seminoma harboring ...

A review indicates shared microRNA regulatory networks serve as molecular bridges connecting pancreatic ductal adenocarcinoma and type 2 diabetes mellitus ...

A combination treatment pairing 1,25-dihydroxyvitamin D3 with astragalus polysaccharide significantly reduced insulin resistance and improved metabolic profiles in rat models ...

Study identifies that MARK2 promotes stem cell characteristics and drug resistance in hepatocellular carcinoma through Wnt and PI3K/AKT signaling.

Researchers demonstrated that a modified traditional herbal formula suppressed human gastric cancer cell growth and induced programmed cell death through ...

An integrated multi-omics and experimental study reveals that estrone from velvet antler promotes osteogenic differentiation in bone marrow stem cells ...

Researchers discovered that administering alpha-ketoglutarate restores blood perfusion and prevents tissue necrosis in ischemic skin flaps by activating the PI3K/Akt/HIF-1alpha ...

A narrative review examines how molecular imaging heterogeneity limits prostate cancer therapy and how artificial intelligence models may assist quantitative ...

A scientific review shows how chemokine CCL5 drives breast cancer progression, metastasis, and immunosuppression while highlighting potential therapeutic targets and ...

Researchers discovered that glutaredoxin 2 deficiency accelerates bone stem cell senescence and osteoporosis by promoting CD36 S-glutathionylation, lipid accumulation, and ...

A scientific review evaluates evidence on how cytomegalovirus may influence cancer stem cells and therapy resistance while noting that tumor ...

In laboratory cell cultures mimicking periodontitis, the natural furanocoumarin bergapten mitigated inflammation and oxidative stress while facilitating bone-forming differentiation in ...

A study in Frontiers in Pharmacology uses network toxicology and molecular docking to identify 16 core targets and key pathways ...

A new study identifies MTFR2 as a key driver of liver cancer progression by activating the PI3K/AKT signaling pathway, offering ...

Bioinformatics analysis identified AKT1 and NF-κB1 as shared molecular targets linking type 2 diabetes, obesity, and hypertension across four core ...

A new study reports that TROP2 suppresses pyroptosis through the PI3K/AKT pathway, promoting hypopharyngeal squamous cell carcinoma progression.