A systematic review examines the cellular mechanisms, pharmacokinetic limitations, and available clinical evidence for the olive oil compound hydroxytyrosol across ...
A narrative review indicates that blood-brain barrier disruption in Alzheimer's disease increases cerebral antipsychotic penetration, triggering parkinsonian side effects and ...
A clinical case series reveals that targeted oral sirolimus therapy induced substantial tumor shrinkage in three neonates with complex head ...
A replicated crossover trial in healthy Chinese volunteers demonstrates that generic vardenafil hydrochloride tablets match branded Levitra in absorption rate ...
A systematic review of 33 clinical studies revealed that food intake primarily alters the rate rather than extent of ADHD ...
A randomized crossover trial in healthy Chinese adults found that extended-release reduced-mass metformin tablets made in a new Chinese facility ...
A new review explains how dapsone remains central to leprosy treatment while its metabolism drives anemia, methemoglobinemia and hypersensitivity risks.
A long-acting engineered version of the amphibian peptide PGLa-AM1, called PGLa-ABD-AFF, showed a roughly 47-hour half-life and improved glucose control, ...
A new review maps how liquid chromatography–tandem mass spectrometry now quantifies drugs, metabolites, genotoxic impurities and proteins across every stage ...
A comprehensive review of naloxone's chemistry, receptor pharmacology and clinical pharmacokinetics explains why the lifesaving opioid antagonist acts so quickly ...
A new review argues that veterinary drug residues persist through cooking and fermentation, while emerging detection technologies remain too immature ...
A harm reduction journal article outlines a practical framework for dissolving psychoactive powders in sterile saline and delivering them with ...
A new Fc-free CLDN18.2 × CD3 bispecific antibody called AHT-102 showed dose-dependent tumor suppression, tumor-selective tissue distribution, and no systemic ...
A pharmacokinetic study in 48 healthy cats found the GLP-1/GIP dual agonist HDM7006 has a roughly 44-hour half-life, dose-proportional exposure ...
A multicenter randomized trial in China found that a single 32 mg intravenous dose of aprepitant given before anesthesia induction ...
A randomized crossover trial in 56 healthy Chinese participants found a generic 800-mg piracetam tablet bioequivalent to the reference product ...
A tailored continuous low-dose iohexol infusion protocol reached a stable plateau within 120 minutes in anesthetized pigs and measured glomerular ...
Two Phase I studies found that a single 10 mg dose of iclepertin raised drug exposure in severe renal and ...
A small clinical trial found an oral transmucosal ketamine lozenge was successfully administered in only 54 percent of doses in ...
A new review explains how neutrophil, complement, and barrier defects reshape antibiotic activity in immunocompromised patients with resistant bacterial infections.
