Genetic Markers May Predict PPI Response in Pediatric EoE
A new study identifies CHST3 genetic variants and food allergy as potential predictors of proton pump inhibitor response in children ...
Tag: Pharmacogenomics
Precision Pharmacovigilance Merges Genomics and Real World Data to Protect Patients
A comprehensive review outlines how integrating proactive pharmacogenomic testing with real-world pharmacovigilance can transform drug safety and prevent adverse reactions.
Immune Markers May Flag Which Psoriasis Patients Respond Best to Ustekinumab
A retrospective study of 42 Chinese patients links the HLA-C*06:02 allele and elevated baseline IgE to faster and deeper skin ...
Host Genomics Could Reshape How Doctors Diagnose Immune Disorders and Treat Infections
More than 30 experts outline how patients' germline genomes could improve infectious disease care, from detecting rare immune disorders early ...
Genetic Testing Could Reshape Emergency Prescribing, but the Evidence Is Not There Yet
A new perspective argues that pharmacogenomic testing could improve emergency department prescribing, but no randomized controlled trials have yet tested ...
Genes and gut microbes shape who tolerates GLP-1 drugs, but never together
Nausea, vomiting, diarrhea and constipation are the price many people pay for the remarkable weight loss and blood sugar control ...
Exome and Array Data Combined Rival Whole-Genome Sequencing for Most Pharmacogenes
Combining whole-exome sequencing with imputed genotyping array data matched whole-genome sequencing results for 25 of 33 pharmacogenes in UK Biobank ...
Molecular obesity therapies advance, but precision prescribing remains largely unproven
A 2026 review finds that multi-agonist obesity drugs can produce substantial weight loss, but biomarker and pharmacogenomic tools are not ...
Large Language Models Could Help Detect Pharmacogenomic Phenoconversion
A 2026 perspective proposes that large language models could integrate genetic and clinical records to identify possible pharmacogenomic phenoconversion, while ...
Model finds CYP2C19-guided DAPT cost-effective after PCI
A 40-year NHS cost-effectiveness model estimated that CYP2C19-guided dual antiplatelet therapy after PCI was likely cost-effective for STEMI and UA/NSTEMI ...
Inflammation Gene Variant May Shape Survival After Rectal Cancer Therapy Choice
An exploratory analysis of a randomized trial in locally advanced rectal cancer found that an IL1B gene variant was linked ...
Long-Read Genome Sequencing Powers a New, Deeply Characterized iPSC Resource for Lab Modeling
Researchers at the Coriell Institute have created a publicly available iPSC resource with HiFi long-read whole-genome sequencing, pharmacogenomic and HLA ...
Pharmacogenomics and Chronotherapy Boost Heart Attack Protection
In a groundbreaking study set to redefine acute myocardial infarction treatment, researchers have uncovered a compelling interplay between pharmacogenomics and ...
Personalized Medicine Progress: Pharmacogenomics Breakthroughs at Ochsner Health
In recent years, the realm of precision medicine has witnessed transformative advancements, with pharmacogenomics emerging at the forefront of this ...
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