Insights in the search for new antibiotics
Credit: Zhao, S., Adamiak, J.W., Bonifay, V. et al. Defining new chemical space for drug penetration into Gram-negative bacteria. Nat ...
Tag: Pharmaceutical Science
A novel drug target for neonatal and infant heart failure
Credit: Mitsuhiko Yamada MD, PhD., Department of Molecular Pharmacology, Shinshu University School of Medicine, Japan Researchers have identified a new ...
Texas Heart Institute to participate in global stem cell study to treat ARDS due to COVID
Cell therapy trial for ICU patients with Acute Respirator Distress Syndrome due to COVID-19Credit: Texas Heart Institute Texas Heart Institute ...
Machine learning innovation to develop chemical library
One-step multicomponent reaction with interpretable machine learning innovation to develop chemical library for drug discoveryCredit: Purdue University/Gaurav Chopra WEST LAFAYETTE, ...
Financial penalties imposed on large pharmaceutical firms for illegal activities
UNC Charlotte research shows price pharmaceutical firms pay for illegal practicesCredit: UNC Charlotte Some pharmaceutical companies have received criticism for ...
Promising results from in vitro combination therapy against COVID-19
Credit: Martin Stenmark. Researchers at Karolinska Institutet in Sweden report promising results from an in vitro combination therapy against COVID-19. ...
New molecules derived from cannabidiol are designed with more potent antioxidants
Credit: Universidad de Córdoba Nowadays, cannabidiol is a star component, not only in the world of cosmetics, but also in ...
Genetic code evolution and Darwin’s evolution theory should consider DNA an ‘energy code’
'Survival of the fittest' phenomenon is only part of the evolution equationCredit: David S. Goodsell and RCSB PDB Darwin's theory ...
Worms reveal why melatonin promotes sleep
Research in C. elegans shows how melatonin activates the BK channel in the brainCredit: Bojun Chen/UConn Health Melatonin is used ...
Baricitinib treatment linked to reduced mortality in COVID-19 patients
Credit: Jannis Politidis The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to ...
Two anti-inflammatory compounds shown to be capable of accelerating recovery from COVID-19
Monoclonal antibody tested by researchers at University of São Paulo and experimental drug given to patients in Italy by University ...
Antidepressant may prevent severe COVID-19, trial suggests
Credit: Dan Addison | UVA Communications The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep ...
Rise in antibiotics prescribed to dental patients in England during COVID-19 lockdown
FDI World Dental Federation (FDI) releases new White Paper on antibiotic resistance to mark World Antimicrobial Awareness WeekCredit: FDI World ...
Predicting the risk of severe side effects of cancer treatment
Credit: Magnus Johansson/Linköping University The risk of serious adverse effects on the blood status and bone marrow of patients during ...
JNCCN study evaluates cost-effectiveness of olaparib for metastatic pancreatic cancer
Data from the POLO trial was analyzed to determine which patient groups with pancreatic cancer would derive the most benefit ...
Fluvoxamine may prevent serious illness in COVID-19 patients
Antidepressant drug repurposed for patients with coronavirus infectionCredit: Matt Miller In a preliminary study of COVID-19 patients with mild-to-moderate disease ...
A therapeutic option for glioblastoma using pH-sensitive nanomicelles
Credit: 2020 Innovation Center of NanoMedicine Summary: Using practical nano-DDS technology, a polymeric nanomicelle that effectively delivers the potent mitotic ...
A molecule from gut bacteria reduces effect of diabetes medication
Credit: Photo by Johan Wingborg. The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, ...
Sorting out viruses with machine learning
Scientists at Osaka University develop a label-free method for identifying respiratory viruses based on changes in electrical current when they ...
Targeted therapies developed to reduce lung fibrosis
Credit: Philip Low/Purdue University WEST LAFAYETTE, Ind. - A new treatment option for lung fibrosis is being developed by Purdue ...