Drug compound could be next-generation treatment for aggressive form of leukemia
Compounds show promise in treating acute myeloid leukemiaCredit: (Purdue Research Foundation image/Hope Sale) WEST LAFAYETTE, Ind. - Researchers have been ...
Tag: Pharmaceutical/Combinatorial Chemistry
Researchers create 'shortcut' to terpene biosynthesis in E. coli
Researchers from North Carolina State University have developed an artificial enzymatic pathway for synthesizing isoprenoids, or terpenes, in E. coli. ...
Nebraska leads $11 million study to develop radiation exposure drugs
Credit: Craig Chandler | University of Nebraska-Lincoln The U.S. Department of Defense has turned to the University of Nebraska to ...
Chirality in 'real-time'
Credit: M. Oppermann, EPFL In nature, certain molecules with the same chemical composition, can exist in two different shapes that ...
How drugs can minimize the side effects of chemotherapy
Researchers at the University of Zurich have determined the three-dimensional structure of the receptor that causes nausea and vomiting as ...
Capturing chemotherapy drugs before they can cause side effects
Credit: Hee Jeung Oh Although chemotherapy can kill cancer cells very effectively, healthy cells also suffer. If doctors could remove ...
Lack of standard dosage for blood thinners can lead to bleeding during bariatric surgery
The study suggests better measures for accurate dosages of blood thinners in obese patientsCredit: Nick Romanenko/Rutgers University Rutgers researchers have ...
University and Boehringer Ingelheim provide free access to PROTAC compound on opnMe.com
Boehringer Ingelheim to make BET degrader compound MZ 1 available through its opnMe.com portalCredit: University of Dundee Boehringer Ingelheim to ...
How baby aspirin saves lives (video)
Credit: The American Chemical Society WASHINGTON, Jan. 3, 2019 -- Low-dose "baby" aspirin is rarely given to children anymore. Instead, ...
Is very low LDL-C harmful?
This article by Dr. Charles Faselis et al. is published in Current Pharmaceutical Design, Volume 24 , Issue 31 , ...
Exploration of umbelliferone based derivatives as potent MAO inhibitors
This article by Dr. Anurag Khatkar et al. is published in Current Topics in Medicinal Chemistry, 2018. Monoamine oxidase (MAO) ...
Role of PCSK9 inhibitors in high risk patients with dyslipidemia
This article by Dr. Vasilios Papademetriou et al. is published in Current Pharmaceutical Design, Volume 24 , Issue 31 , ...
Lipo-protein apheresis and PCSK9-inhibitors
This article by Dr. Claudia Stefanutti et al. is published in Current Pharmaceutical Design, Volume 24 , Issue 31 , ...
Anti-obesity Drug Discovery and Development
Atta-ur-Rahman; published on Dec 14, 2018, Volume 4 Obesity is a complex health problem, caused by a number of factors ...
Unmuting large silent genes lets bacteria produce new molecules, potential drug candidates
Credit: Photo by L. Brian Stauffer CHAMPAIGN, Ill. -- By enticing away the repressors dampening unexpressed, silent genes in Streptomyces ...
Genetic polymorphisms and zinc status
This article by Dr. Angela Polito et al. is published in Current Pharmaceutical Design, 2018 Zinc is one of the ...
Computational advances in the label-free quantification of cancer proteomics data
This article by Dr. Feng Zhu et al. is published in Current Pharmaceutical Design, 2018 In recent years, proteomics research ...
Predicting enhancers from multiple cell lines and tissues: Different developmental stages
This article by Dr. Jihong Guan et al. is published in Current Bioinformatics, Volume 13, Issue 6, 2018Credit: Bentham Science ...
Bacteria-based drug delivery system that outperforms conventional methods
Credit: Virginia Tech An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created ...
Central role of transforming growth factor type beta 1 in skeletal muscle dysfunctions
This article by Dr. Claudio Cabello-Verrugio et al. is published in Current Protein & Peptide Science, Volume 19, Issue 12, ...