A heart failure drug to treat leukemia: A promising new therapeutic approach
Canadian researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. Those ...
Tag: Pharmaceutical Chemistry
A homing beacon for chemotherapy drugs
Credit: Adapted from ACS Central Science 2019, DOI: 10.1021/acscentsci.9b00195 Killing tumor cells while sparing their normal counterparts is a central ...
Opioid alternative? Taming tetrodotoxin for precise painkilling
Findings in rats suggest that a pufferfish toxin, properly packaged, could offer a safe pain blockCredit: Opioids remain a mainstay ...
New vulnerability found in major human viruses
Structural feature may lead to antivirals for the common cold, polio, and other pathogensCredit: James Geraets Discovery of a new ...
Learning from nature’s bounty: New libraries for drug discovery
Credit: Image: University of Basel, Basilius Sauter | CC BY-SA 3.0 Natural products, or their close derivatives, make some of ...
Promising treatment option for Complex Regional Pain Syndrome
A study, published today in PNAS, has found a potential treatment for patients with Complex Regional Pain Syndrome (CRPS). CRPS ...
Nitric oxide-scavenging hydrogel developed for rheumatoid arthritis treatment
Professor Won Jong Kim and his research team developed a nano-sized hydrogel that treats inflammatory disease by scavenging nitric oxideCredit: ...
Researchers develop breakthrough process to create cancer-killing drugs
New technique could produce treatments for wide variety of diseasesCredit: Glenn Micalizio HANOVER, N.H. - June 4, 2019 - A ...
A fast all-visible-light molecular switch with 100 nm band separation
De novo design allows for breakthrough in molecular photocontrolCredit: Wiktor Szymanski, University of Groningen Medical Center. A consortium of scientists ...
HGF-inhibitory macrocyclic peptide — mechanisms and potential cancer theranostics
Credit: Kanazawa University Background Hepatocyte Growth Factor (HGF)*1) is a protein that acts as a cell growth factor. By binding ...
Synthetic version of CBD treats seizures in rats
Credit: Mascal laboratory, UC Davis A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according ...
Reducing the destruction of heart failure
Too much adrenaline causes heart to decrease functionCredit: University of Houston A University of Houston College of Pharmacy researcher is ...
Developing biosecurity tool to detect genetically engineered organisms in the wild
With scientists from Raytheon and other universities, WPI chemical engineer Eric Young is helping develop a method for using DNA ...
Rare pulmonary side effects of brigatinib often resolve without treatment discontinuation
Credit: University of Colorado Cancer Center Brigatinib is a next-generation ALK inhibitor that earned FDA approval in 2017 as a ...
Using 3D to test personalised treatments in five days
UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best ...
June’s SLAS technology special collection now available
Sample management collection features 'next generation compound delivery to support miniaturized biology'Credit: David James Group Oak Brook, IL - The ...
SLAS Discovery announces its June cover article
SLAS Discovery announces its June cover article, 'A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction'Credit: David James ...
New technology to revolutionize drug development
Collaboration aims to create 3D images of cells in high resolution The search for new drugs to combat diseases more ...
Researchers identify faster, more effective drug combinations to treat tuberculosis
Credit: D.L. Clemens Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, ...
MDI biological laboratory receives $30,000 to support organoid course
Course will provide extensive laboratory training in organoid technologyCredit: Leif Oxburgh Laboratory at the Maine Medical Center Research Institute. BAR ...