Endometrial cancer clinical trial aims to pave the way for practice-changing therapy
Credit: University of Colorado Cancer Center The University of Colorado Cancer Center is leading the way in the development of ...
Tag: Pharmaceutical Chemistry
How a popular antidepressant drug could rewire the brain
Prozac®, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in ...
New antibacterial fillings from Tel Aviv University may combat recurring tooth decay
Novel material may prevent one of the costliest and most prevalent bacterial diseases in the world Tooth decay is among ...
Small-volume, high-throughput organic synthesis
New method synthesizes and evaluates large number of drug leadsCredit: Neochoritis et al. / Science Advances University of Groningen Professor ...
Treatment target pinpointed for liver cancer in teens and young adults
The suspect, an abnormal, fused protein, gathers enzymes that drive uncontrolled cell growthCredit: Mitchell H. Omar New findings show how ...
Combining antibiotics, researchers deliver one-two punch against ubiquitous bacterium
CWRU/Cleveland VA findings in mouse models could make inroads against superbugs By combining two well-established antibiotics for the first time, ...
Fighting drug resistance with fast, artificial enhancement of natural products
Credit: Image by Caitlin Devor, The University of Tokyo, CC-BY Researchers in Japan have identified multiple promising new drug candidates ...
Most powerful and mildest reagents obtained based on eco-friendly iodine
How iodine state enables organic synthesis at room temperatureCredit: Tomsk Polytechnic University An international collaboration of chemists from Tomsk Polytechnic ...
Scientists invent fast method for ‘directed evolution’ of molecules
The technique, dubbed VEGAS, works in mammalian cells and can yield useful new molecules within days, providing scientist with a ...
Dose-dependent effects of esmolol-epinephrine combination therapy in myocardial ischemia
The article by Dr. Tobias Eckle et al. is published in Current Pharmaceutical Design, Volume 25, 2019 Epinephrine has been ...
Future Drug Discovery publishes its first issue
Future Science Group (FSG) is pleased to announce the publication of the first issue of its new open access journal, ...
Synthesizing chemical-sensing cells from scratch
Credit: OIST Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from ...
Medicines made of solid gold to help the immune system
By studying the effects of gold nanoparticles on the immune cells related to antibody production, researchers at UNIGE, at Swansea ...
Confining cell-killing treatments to tumors
Attaching a Velcro-like molecule may prevent immune proteins called cytokines from leaking out of cancerous tissue after injection Cytokines, small ...
Common antidepressants interact with opioid med to lessen pain relief
Findings from University Hospitals study could help explain certain apparent opioid drug-seeking behavior and opioid overuse CLEVELAND -- Common antidepressants ...
New therapy promotes vascular repair following stroke
Credit: Illustration: Ruslan Rust Following a stroke, antibodies that inhibit the signaling molecule Nogo-A can help repair blood vessels in ...
Chemists discover structure of glucagon fibrils
Study may be a step toward shelf-stable versions of the hormone, which is used to control diabetes. Patients with type ...
Immunotherapy and HDAC inhibition are anti-cancer besties
Credit: University of Colorado Cancer Center Immunotherapies have revolutionized the care of many cancers, teaching the body's own immune cells ...
CityU receives grand challenges explorations grant for research in global health
To investigate the growth of multiple strains of human gut microbes in a single reactorCredit: City University of Hong Kong ...
Preventing drugs from being transported
Certain membrane proteins specialize in transporting molecules out of cells -- a problem for the efficacy of cancer medication and ...