METS-IR and TyG-BMI Accurately Detect Steatotic Liver Disease in PCOS
A retrospective study showed that the METS-IR and TyG-BMI indices demonstrated high and comparable performance in identifying metabolic dysfunction-associated steatotic ...
Tag: PCOS
Liensinine targets ATG9B to curb autophagy dysfunction in PCOS models
Researchers found that the natural compound liensinine binds ATG9B to modulate AKT/mTOR signalling and reduce excessive autophagy in PCOS cell ...
KISS1 gene variants linked to PCOS risk across multiple populations, review finds
A systematic review of 26 studies links KISS1 gene polymorphisms, particularly rs4889, to polycystic ovary syndrome susceptibility and hormonal dysregulation ...
Alcohol, nicotine and cannabis each reshape PCOS biology in distinct ways, review finds
A review of 87 studies links chronic alcohol use, nicotine exposure and weekly cannabis consumption to distinct hormonal and metabolic ...
Scientists Link Immune Genes and Iron-Driven Cell Death to PCOS
A new bioinformatics and experimental study identifies twelve candidate genes for polycystic ovary syndrome and shows that the metabolic enzyme ...
Probiotics, Prebiotics and Synbiotics Show Broad Metabolic and Hormonal Benefits in PCOS Meta-Analysis
A meta-analysis of twenty randomized controlled trials and an umbrella review of eleven meta-analyses finds that prebiotics, probiotics, and synbiotics ...
Ovarian circular DNA shows reduced abundance in PCOS rat model
Circle sequencing of ovaries from a rat model of polycystic ovary syndrome identified more than 15,000 extrachromosomal circular DNA molecules, ...
PCOS reframed as PMOS: fetal programming, epigenetics and puberty’s second hit
A new review proposes that polyendocrine metabolic ovarian syndrome arises from prenatal epigenetic programming that is unmasked by puberty and ...
Oocyte–granulosa cell communication networks linked to follicular development and ovarian disorders in new review
A new open-access review in the Journal of Ovarian Research maps how oocyte–granulosa cell communication networks coordinate follicular development and ...
PCOS Phenotypes Show Similar ART Pregnancy Outcomes, Study Finds
A retrospective study of 1,377 PCOS patients undergoing ART found comparable pregnancy and neonatal outcomes across the four Rotterdam phenotypes, ...
No Link Found Between PCOS, Personality Traits and Mediterranean Diet Adherence in Infertile Women
A case-control study of 180 infertile women found no statistically significant associations between polycystic ovary syndrome, personality traits, and adherence ...
Jordanian women with PCOS show heavier anxiety, depression and skin burden
A cross-sectional study at a Jordanian tertiary hospital found that 276 women with PCOS reported significantly higher anxiety, depressive symptoms, ...
Two Gene Variants Linked to PCOS Risk in Pakistani Women in Case-Control Study
A hospital-based case-control study in Lahore found that a variant in the FSHR gene was strongly associated with polycystic ovary ...
Gut microbe metabolite worsens PCOS-like ovarian dysfunction under metabolic stress
A study links the gut bacterium Bacteroides fragilis and its metabolite indole-3-acetic acid to PCOS-like ovarian abnormalities that emerge only ...
Heart Health Across a Woman’s Lifetime: New Guidance Links Hormones, Mind and Cardiovascular Risk
A new American Heart Association-led series in Circulation outlines a female-specific life-course approach connecting hormonal changes, mental health and cardiovascular ...
New framework puts women’s heart disease prevention at puberty’s doorstep
Four leading medical societies have jointly published a female life stage framework that anchors cardiovascular prevention to hormonal transitions beginning ...
Stem cells wrapped in hydrogel restore ovarian structure in PCOS rats
Human Wharton's jelly-derived mesenchymal stem cells delivered inside an alginate-gelatin hydrogel improved follicular architecture and lowered inflammatory cytokines in a ...
AMH, Blood Sugar and Weight Combine to Flag Ovarian Syndrome Before Fertility Treatment
A three-variable model combining AMH, the triglyceride-glucose index and BMI showed strong discrimination for flagging PMOS in pre-ART patients, though ...
AI Subtyping Suggests Polycystic Ovarian Syndrome Is Four Distinct Conditions
A review argues that polycystic metabolic ovarian syndrome is best understood as four biologically distinct subtypes identified through multi-omics data ...
Ovarian Hormone Disorder PMOS May Raise Alzheimer’s and Dementia Risk, Review Finds
A new review links polyendocrine metabolic ovarian syndrome, formerly PCOS, to possible elevated risk of Alzheimer's disease and dementia through ...
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