A prospective pilot trial found combining intraarterial and intravenous radionuclide infusions delivered over three times more radiation to liver metastases ...
3D-ring CZT gamma cameras offer faster and more sensitive imaging for targeted radionuclide therapy, enabling better treatment personalization and response ...
In preclinical mouse models of neuroendocrine tumors, a dual-targeting SSTR2 and FAP heterodimer achieved tumor exposure comparable to a homodimer ...
A retrospective study of 178 patients found that integrating the Krenning score with specific laboratory markers improves the accuracy of ...
An in vitro study found that lanthanum-135 labeled DOTA-TATE and DOTA-LM3 delivered insufficient nuclear radiation doses to produce therapeutic effects ...
A retrospective study of 3,573 appendectomy patients found occult appendiceal neoplasms in 1.09% of cases, with older age independently associated ...
A scientific review details the clinical momentum, biological complexity, and dosimetric challenges shaping the next era of precision radiopharmaceutical cancer ...
A new review maps how target-specific radiopharmaceuticals pair matched diagnostic and therapeutic radionuclides to deliver precision cancer therapy from imaging ...
A cross-site multiomic analysis of 194 patients has uncovered three distinct molecular subtypes of neuroendocrine tumors that provide prognostic value ...
In mice bearing SSTR2-H69 xenografts, terbium-161-labeled DOTA-TATE and DOTA-JR11 matched lutetium-177 at 20 Gy tumor dose and outperformed it at ...
A preclinical study reports that combining the serotonin-synthesis inhibitor telotristat ethyl with the mTOR inhibitor everolimus arrested tumor growth in ...
A retrospective study of 642 patients found bone metastases in 37.1 percent of metastatic neuroendocrine tumors and linked them to ...
Researchers in Xi'an have trained a cascaded generative adversarial network to synthesize 18F-FDG PET images from 18F-octreotide scans, achieving near-perfect ...
Proteomic profiling of GOT1 neuroendocrine tumors after lutetium-177 DOTATATE therapy reveals suppressed invasion pathways and altered p53 and stress signaling ...
A new review maps the molecular drivers of pituitary neuroendocrine tumors, evaluates established and emerging drug therapies, and separates clinically ...
A Mayo Clinic analysis of 1,364 cancer patients links distinct gut microbiome patterns to five cancer groups, early-onset colorectal and ...
A new Journal of Nuclear Medicine supplement surveys the theranostics pipeline, from isotope supply and dosimetry to pivotal phase 3 ...
A single-cell RNA sequencing study has revealed that rare ACTH- and CRH-secreting pheochromocytomas harbor a primitive Schwann cell precursor-like tumor ...
Living donor liver transplantation (LDLT) has emerged as a promising alternative in the realm of transplant oncology, particularly for patients ...
