Tag: natural killer cells

A scientific review examines how complex immune cell interactions drive progressive fibrotic remodeling in kidney allografts while highlighting that no ...

A case-control study of Egyptian hepatitis C patients reveals how specific MICA and COMT gene variants, combined with clinical biomarkers, ...

A comprehensive multi-cohort genomic study reveals that lung adenocarcinoma tumors undergo marked natural killer cell depletion and state redistribution away ...

A retrospective study of 145 newly diagnosed diffuse large B-cell lymphoma patients revealed that bone marrow CD4-positive T-cell depletion independently ...

Researchers found that an age-associated retinoid shift alters human natural killer cell biomechanics and impairs immune surveillance, while inhibiting the ...

A patient with severe relapsed and refractory lupus nephritis achieved durable clinical and renal remission following treatment with allogeneic CD19-targeted ...

A translational study reveals that higher predicted donor-recipient HLA epitope mismatch associates with distinct innate immune cell configurations in clinically ...

Researchers have developed an automated immunological scoring tool that significantly improves diagnostic differentiation for patients with chronic upper urinary tract ...

Inhibiting IGF-1R reduces myelodysplastic syndrome cell proliferation, triggers DNA damage, and sensitizes malignant cells to natural killer cell destruction via ...

A multi-omics Mendelian randomization study reveals that the immune protein MICB promotes cerebral atherosclerosis by suppressing the ferroptosis regulator FTMT ...

A synthetic engager targeting the inhibitory NKG2A receptor shields HLA-deficient engineered regulatory T cells from natural killer cell destruction, enabling ...

A multi-omics study identified an eight-gene diagnostic signature and provided statistical genetic evidence linking elevated natural killer cell TPX2 expression ...

A study combining transcriptomic analysis and mouse models reveals that natural killer cells suppress lung metastases across different cancer types ...

New research shows the immune protein perforin can kill tumor cells on its own by triggering iron-dependent ferroptosis, even when ...

Preclinical research shows that natural killer cells engineered with a CD73-targeting receptor kill relapsed or refractory lung adenocarcinoma cells in ...

A scoping review proposes that exercise adaptations may align with triple-negative breast cancer biology, citing preliminary safety and feasibility evidence ...

B7-H6 expression on tumor cells and tumor-infiltrating leukocytes is linked to metastasis, lymph node spread and reduced overall survival in ...

A new narrative review in Frontiers in Oncology details how T cells, macrophages, neutrophils, B cells, NK cells, and dendritic ...

A newly published protocol details a three-component tumor organoid co-culture system with 3D live-cell imaging that quantifies single-cell dynamics of ...

A retrospective study of 126 treatment-naïve idiopathic inflammatory myopathy patients found that pre-treatment lymphocyte subset profiles differed across disease subtypes ...