Tag: natural killer cells

A new review synthesizes engineering strategies and early clinical findings for CAR-NK cell immunotherapy in blood cancers and solid tumors.

Researchers report that SERPINA3 acts as a soluble SIRPα ligand that suppresses immune cells, easing inflammatory disease models while helping ...

A study of 27 chronic hepatitis B patients found that those achieving HBsAg loss on pegylated interferon-alpha and nucleos(t)ide analog ...

A new mini-review outlines how epigenetic silencing of NK-activating ligands helps urothelial carcinoma evade immune attack and how DNMT and ...

Forcing T-BET expression in iPSC-derived NK cells boosted IFN gamma and inflammatory chemokines but left cytotoxic function and terminal maturation ...

A new review argues that natural killer cells in colorectal cancer liver metastasis form a heterogeneous, microenvironment-shaped spectrum of states ...

A new review maps how RNA- and DNA-sensing innate immune pathways determine whether cardiotropic viral infection resolves or progresses to ...

New research from Memorial Sloan Kettering Cancer Center reveals how cohesin activates distant genes, identifies an immunogenic cell death called ...

A review in the Journal of Ovarian Research surveys clinical trial evidence on CAR-T, TCR-T, TIL and NK cell therapies, ...

A study in Journal of Translational Medicine shows that the tumor protein stratifin stabilizes PAK1 and activates MYC-driven NECTIN2 expression, ...

A retrospective cohort study linked enteral nutrition within 24 hours of gastrectomy for gastric cancer with better preservation of selected ...

A 2026 narrative review links inherited HLA class I and class II variation to pediatric neuroblastoma susceptibility and selected outcomes, ...

A clinical protocol review says Intralipid-based immunomodulation may be considered in selected cases of reproductive failure, but routine use is ...

An abstract summarizes in vitro evidence that sLTA enhanced NK-cell activity and sensitized HT-29 colon cancer cells to apoptosis in ...

A nine-patient phase I trial found that TIGIT-disrupted NK510 could be combined with PD-1 blockade without observed dose-limiting toxicities in ...

A mini review finds that microRNAs regulate the immune-surveillance protein MICA and proposes that naturally occurring MICA variants may alter ...

A large Chinese cohort study shows that lymphocyte subsets in women undergo a pronounced reconfiguration around menopause, with B cell ...

Researchers used CRISPR-Cas9 to knock out the TAPBP gene in human induced pluripotent stem cells, producing cardiomyocytes with sharply reduced ...

A new study links baseline IFN-γ-based NK cell activity to ex vivo expansion capacity of autologous NK cells, offering a ...

A new review highlights how induced pluripotent stem cells are being engineered into immune cells, cancer vaccines, and tumor models ...